Morgan BP - Search Results

1

Dimerization of complement factor H-related proteins modulates complement activation in vivo.

Goicoechea de Jorge E, Caesar JJ, Malik TH, Patel M, Colledge M, Johnson S, Hakobyan S, Morgan BP, Harris CL, Pickering MC, Lea SM. Goicoechea de Jorge E, et al. Among authors: morgan bp. Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4685-90. doi: 10.1073/pnas.1219260110. Epub 2013 Mar 4. Proc Natl Acad Sci U S A. 2013. PMID: 23487775 Free PMC article.

2

Molecular dissection of interactions between components of the alternative pathway of complement and decay accelerating factor (CD55).

Harris CL, Abbott RJ, Smith RA, Morgan BP, Lea SM. Harris CL, et al. Among authors: morgan bp. J Biol Chem. 2005 Jan 28;280(4):2569-78. doi: 10.1074/jbc.M410179200. Epub 2004 Nov 9. J Biol Chem. 2005. PMID: 15536079 Free article.

3

Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk.

Heurich M, Martínez-Barricarte R, Francis NJ, Roberts DL, Rodríguez de Córdoba S, Morgan BP, Harris CL. Heurich M, et al. Among authors: morgan bp. Proc Natl Acad Sci U S A. 2011 May 24;108(21):8761-6. doi: 10.1073/pnas.1019338108. Epub 2011 May 9. Proc Natl Acad Sci U S A. 2011. PMID: 21555552 Free PMC article.

4

Structural basis for complement factor I control and its disease-associated sequence polymorphisms.

Roversi P, Johnson S, Caesar JJ, McLean F, Leath KJ, Tsiftsoglou SA, Morgan BP, Harris CL, Sim RB, Lea SM. Roversi P, et al. Among authors: morgan bp. Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12839-44. doi: 10.1073/pnas.1102167108. Epub 2011 Jul 18. Proc Natl Acad Sci U S A. 2011. PMID: 21768352 Free PMC article.

5

Complement and complement regulators in the male reproductive system.

Harris CL, Mizuno M, Morgan BP. Harris CL, et al. Among authors: morgan bp. Mol Immunol. 2006 Jan;43(1-2):57-67. doi: 10.1016/j.molimm.2005.06.026. Mol Immunol. 2006. PMID: 16023728 Review.

6

Decay-accelerating factor must bind both components of the complement alternative pathway C3 convertase to mediate efficient decay.

Harris CL, Pettigrew DM, Lea SM, Morgan BP. Harris CL, et al. Among authors: morgan bp. J Immunol. 2007 Jan 1;178(1):352-9. doi: 10.4049/jimmunol.178.1.352. J Immunol. 2007. PMID: 17182573

7

Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome.

Goicoechea de Jorge E, Harris CL, Esparza-Gordillo J, Carreras L, Arranz EA, Garrido CA, López-Trascasa M, Sánchez-Corral P, Morgan BP, Rodríguez de Córdoba S. Goicoechea de Jorge E, et al. Among authors: morgan bp. Proc Natl Acad Sci U S A. 2007 Jan 2;104(1):240-5. doi: 10.1073/pnas.0603420103. Epub 2006 Dec 20. Proc Natl Acad Sci U S A. 2007. PMID: 17182750 Free PMC article.

8

Functional basis of protection against age-related macular degeneration conferred by a common polymorphism in complement factor B.

Montes T, Tortajada A, Morgan BP, Rodríguez de Córdoba S, Harris CL. Montes T, et al. Among authors: morgan bp. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4366-71. doi: 10.1073/pnas.0812584106. Epub 2009 Mar 2. Proc Natl Acad Sci U S A. 2009. PMID: 19255449 Free PMC article.

9

Identification of factor H-like protein 1 as the predominant complement regulator in Bruch's membrane: implications for age-related macular degeneration.

Clark SJ, Schmidt CQ, White AM, Hakobyan S, Morgan BP, Bishop PN. Clark SJ, et al. Among authors: morgan bp. J Immunol. 2014 Nov 15;193(10):4962-70. doi: 10.4049/jimmunol.1401613. Epub 2014 Oct 10. J Immunol. 2014. PMID: 25305316 Free PMC article.

10

Complement, a target for therapy in inflammatory and degenerative diseases.

Morgan BP, Harris CL. Morgan BP, et al. Nat Rev Drug Discov. 2015 Dec;14(12):857-77. doi: 10.1038/nrd4657. Epub 2015 Oct 23. Nat Rev Drug Discov. 2015. PMID: 26493766 Free PMC article. Review.

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