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Page 1
Exploration of the structure-activity relationship of a novel tetracyclic class of TSPO ligands-potential novel positron emitting tomography imaging agents.
O'Shea D, Ahmad R, Årstad E, Avory M, Chau WF, Durrant C, Hirani E, Jones PA, Khan I, Luthra SK, Mantzilas D, Morisson-Iveson V, Passmore J, Robins EG, Shan B, Wadsworth H, Walton S, Zhao Y, Trigg W. O'Shea D, et al. Among authors: chau wf. Bioorg Med Chem Lett. 2013 Apr 15;23(8):2368-72. doi: 10.1016/j.bmcl.2013.02.057. Epub 2013 Feb 24. Bioorg Med Chem Lett. 2013. PMID: 23489633
[¹⁸F]GE-180: a novel fluorine-18 labelled PET tracer for imaging Translocator protein 18 kDa (TSPO).
Wadsworth H, Jones PA, Chau WF, Durrant C, Fouladi N, Passmore J, O'Shea D, Wynn D, Morisson-Iveson V, Ewan A, Thaning M, Mantzilas D, Gausemel I, Khan I, Black A, Avory M, Trigg W. Wadsworth H, et al. Among authors: chau wf. Bioorg Med Chem Lett. 2012 Feb 1;22(3):1308-13. doi: 10.1016/j.bmcl.2011.12.084. Epub 2011 Dec 27. Bioorg Med Chem Lett. 2012. PMID: 22244939
Exploration of the structure-activity relationship of the diaryl anilide class of ligands for translocator protein--potential novel positron emitting tomography imaging agents.
Wadsworth H, Jones PA, Chau WF, Durrant C, Morisson-Iveson V, Passmore J, O'Shea D, Wynn D, Khan I, Black A, Avory M, Trigg W. Wadsworth H, et al. Among authors: chau wf. Bioorg Med Chem Lett. 2012 Sep 15;22(18):5795-800. doi: 10.1016/j.bmcl.2012.07.093. Epub 2012 Aug 3. Bioorg Med Chem Lett. 2012. PMID: 22902658
Evaluation of a novel series of fluorine-18-labeled imidazobenzodiazepines as potential new positron emission tomography radioligands for the GABAA receptor.
Jackson A, Battle MR, O'Shea DM, Chau WF, Gaeta A, Brown SL, Ewan AL, Jones CL, Jones PA, Woodcraft JL, Bouvet DR, Guilbert BB, Trigg W. Jackson A, et al. Among authors: chau wf. Nucl Med Biol. 2014 Feb;41(2):196-202. doi: 10.1016/j.nucmedbio.2013.11.010. Epub 2013 Dec 7. Nucl Med Biol. 2014. PMID: 24480268