Brentjens RJ - Search Results

1

CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia.

Brentjens RJ, Davila ML, Riviere I, Park J, Wang X, Cowell LG, Bartido S, Stefanski J, Taylor C, Olszewska M, Borquez-Ojeda O, Qu J, Wasielewska T, He Q, Bernal Y, Rijo IV, Hedvat C, Kobos R, Curran K, Steinherz P, Jurcic J, Rosenblat T, Maslak P, Frattini M, Sadelain M. Brentjens RJ, et al. Sci Transl Med. 2013 Mar 20;5(177):177ra38. doi: 10.1126/scitranslmed.3005930. Sci Transl Med. 2013. PMID: 23515080 Free PMC article. Clinical Trial.

2

Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRzeta /CD28 receptor.

Maher J, Brentjens RJ, Gunset G, Rivière I, Sadelain M. Maher J, et al. Among authors: brentjens rj. Nat Biotechnol. 2002 Jan;20(1):70-5. doi: 10.1038/nbt0102-70. Nat Biotechnol. 2002. PMID: 11753365

3

Targeting tumours with genetically enhanced T lymphocytes.

Sadelain M, Rivière I, Brentjens R. Sadelain M, et al. Nat Rev Cancer. 2003 Jan;3(1):35-45. doi: 10.1038/nrc971. Nat Rev Cancer. 2003. PMID: 12509765 Review.

4

Eradication of systemic B-cell tumors by genetically targeted human T lymphocytes co-stimulated by CD80 and interleukin-15.

Brentjens RJ, Latouche JB, Santos E, Marti F, Gong MC, Lyddane C, King PD, Larson S, Weiss M, Rivière I, Sadelain M. Brentjens RJ, et al. Nat Med. 2003 Mar;9(3):279-86. doi: 10.1038/nm827. Epub 2003 Feb 10. Nat Med. 2003. PMID: 12579196

5

Novel strategies for cancer therapy: the potential of genetically modified T lymphocytes.

Rivière I, Sadelain M, Brentjens RJ. Rivière I, et al. Among authors: brentjens rj. Curr Hematol Rep. 2004 Jul;3(4):290-7. Curr Hematol Rep. 2004. PMID: 15217559 Review.

6

Somatic cell engineering and the immunotherapy of leukemias and lymphomas.

Brentjens RJ, Sadelain M. Brentjens RJ, et al. Adv Pharmacol. 2004;51:347-70. doi: 10.1016/S1054-3589(04)51015-3. Adv Pharmacol. 2004. PMID: 15464917 Review. No abstract available.

7

Targeted elimination of prostate cancer by genetically directed human T lymphocytes.

Gade TP, Hassen W, Santos E, Gunset G, Saudemont A, Gong MC, Brentjens R, Zhong XS, Stephan M, Stefanski J, Lyddane C, Osborne JR, Buchanan IM, Hall SJ, Heston WD, Rivière I, Larson SM, Koutcher JA, Sadelain M. Gade TP, et al. Cancer Res. 2005 Oct 1;65(19):9080-8. doi: 10.1158/0008-5472.CAN-05-0436. Cancer Res. 2005. PMID: 16204083

8

Pentostatin, cyclophosphamide, and rituximab is an active, well-tolerated regimen for patients with previously treated chronic lymphocytic leukemia.

Lamanna N, Kalaycio M, Maslak P, Jurcic JG, Heaney M, Brentjens R, Zelenetz AD, Horgan D, Gencarelli A, Panageas KS, Scheinberg DA, Weiss MA. Lamanna N, et al. J Clin Oncol. 2006 Apr 1;24(10):1575-81. doi: 10.1200/JCO.2005.04.3836. Epub 2006 Mar 6. J Clin Oncol. 2006. PMID: 16520464

9

Genetically targeted T cells eradicate systemic acute lymphoblastic leukemia xenografts.

Brentjens RJ, Santos E, Nikhamin Y, Yeh R, Matsushita M, La Perle K, Quintás-Cardama A, Larson SM, Sadelain M. Brentjens RJ, et al. Clin Cancer Res. 2007 Sep 15;13(18 Pt 1):5426-35. doi: 10.1158/1078-0432.CCR-07-0674. Epub 2007 Sep 12. Clin Cancer Res. 2007. PMID: 17855649

10

T cell-encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection.

Stephan MT, Ponomarev V, Brentjens RJ, Chang AH, Dobrenkov KV, Heller G, Sadelain M. Stephan MT, et al. Among authors: brentjens rj. Nat Med. 2007 Dec;13(12):1440-9. doi: 10.1038/nm1676. Epub 2007 Nov 18. Nat Med. 2007. PMID: 18026115

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