Olcina MM - Search Results

1

Optimization of 3,5-dimethylisoxazole derivatives as potent bromodomain ligands.

Hewings DS, Fedorov O, Filippakopoulos P, Martin S, Picaud S, Tumber A, Wells C, Olcina MM, Freeman K, Gill A, Ritchie AJ, Sheppard DW, Russell AJ, Hammond EM, Knapp S, Brennan PE, Conway SJ. Hewings DS, et al. Among authors: olcina mm. J Med Chem. 2013 Apr 25;56(8):3217-27. doi: 10.1021/jm301588r. Epub 2013 Apr 5. J Med Chem. 2013. PMID: 23517011 Free PMC article.

2

Targeting hypoxic cells through the DNA damage response.

Olcina M, Lecane PS, Hammond EM. Olcina M, et al. Clin Cancer Res. 2010 Dec 1;16(23):5624-9. doi: 10.1158/1078-0432.CCR-10-0286. Epub 2010 Sep 27. Clin Cancer Res. 2010. PMID: 20876254 Free PMC article. Review.

3

Targeting radiation-resistant hypoxic tumour cells through ATR inhibition.

Pires IM, Olcina MM, Anbalagan S, Pollard JR, Reaper PM, Charlton PA, McKenna WG, Hammond EM. Pires IM, et al. Among authors: olcina mm. Br J Cancer. 2012 Jul 10;107(2):291-9. doi: 10.1038/bjc.2012.265. Epub 2012 Jun 19. Br J Cancer. 2012. PMID: 22713662 Free PMC article.

4

Targeting ATR in vivo using the novel inhibitor VE-822 results in selective sensitization of pancreatic tumors to radiation.

Fokas E, Prevo R, Pollard JR, Reaper PM, Charlton PA, Cornelissen B, Vallis KA, Hammond EM, Olcina MM, Gillies McKenna W, Muschel RJ, Brunner TB. Fokas E, et al. Among authors: olcina mm. Cell Death Dis. 2012 Dec 6;3(12):e441. doi: 10.1038/cddis.2012.181. Cell Death Dis. 2012. PMID: 23222511 Free PMC article.

5

CH-01 is a hypoxia-activated prodrug that sensitizes cells to hypoxia/reoxygenation through inhibition of Chk1 and Aurora A.

Cazares-Körner C, Pires IM, Swallow ID, Grayer SC, O'Connor LJ, Olcina MM, Christlieb M, Conway SJ, Hammond EM. Cazares-Körner C, et al. Among authors: olcina mm. ACS Chem Biol. 2013 Jul 19;8(7):1451-9. doi: 10.1021/cb4001537. Epub 2013 May 10. ACS Chem Biol. 2013. PMID: 23597309 Free PMC article.

6

Replication stress and chromatin context link ATM activation to a role in DNA replication.

Olcina MM, Foskolou IP, Anbalagan S, Senra JM, Pires IM, Jiang Y, Ryan AJ, Hammond EM. Olcina MM, et al. Mol Cell. 2013 Dec 12;52(5):758-66. doi: 10.1016/j.molcel.2013.10.019. Epub 2013 Nov 21. Mol Cell. 2013. PMID: 24268576 Free PMC article.

7

WIP1 and senescence: oxygen matters.

Olcina MM, Hammond EM. Olcina MM, et al. Cell Cycle. 2014;13(7):1062. doi: 10.4161/cc.28385. Epub 2014 Feb 28. Cell Cycle. 2014. PMID: 24584094 Free PMC article. No abstract available.

8

Targeting chromatin to improve radiation response.

Olcina MM, O'Dell S, Hammond EM. Olcina MM, et al. Br J Radiol. 2015 Mar;88(1047):20140649. doi: 10.1259/bjr.20140649. Epub 2014 Dec 16. Br J Radiol. 2015. PMID: 25513745 Free PMC article. Review.

9

H3K9me3 facilitates hypoxia-induced p53-dependent apoptosis through repression of APAK.

Olcina MM, Leszczynska KB, Senra JM, Isa NF, Harada H, Hammond EM. Olcina MM, et al. Oncogene. 2016 Feb 11;35(6):793-9. doi: 10.1038/onc.2015.134. Epub 2015 May 11. Oncogene. 2016. PMID: 25961932 Free PMC article.

10

Mechanisms and consequences of ATMIN repression in hypoxic conditions: roles for p53 and HIF-1.

Leszczynska KB, Göttgens EL, Biasoli D, Olcina MM, Ient J, Anbalagan S, Bernhardt S, Giaccia AJ, Hammond EM. Leszczynska KB, et al. Among authors: olcina mm. Sci Rep. 2016 Feb 15;6:21698. doi: 10.1038/srep21698. Sci Rep. 2016. PMID: 26875667 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

30 results

Search Page

Filters