Schmitt C - Search Results

1

Pharmacological control of platelet-leukocyte interactions by the human anti-P-selectin antibody inclacumab--preclinical and clinical studies.

Kling D, Stucki C, Kronenberg S, Tuerck D, Rhéaume E, Tardif JC, Gaudreault J, Schmitt C. Kling D, et al. Among authors: schmitt c. Thromb Res. 2013 May;131(5):401-10. doi: 10.1016/j.thromres.2013.02.020. Epub 2013 Mar 21. Thromb Res. 2013. PMID: 23522853

2

Safety, pharmacokinetics and pharmacodynamics of multiple ascending doses of R1663, an oral factor Xa inhibitor, in healthy young subjects coupled with exploration of influence of gender and age.

Schmitt C, Charoin-Pannier A, McIntyre C, Zandt H, Ciorciaro C, Winters K, Pepper T. Schmitt C, et al. Thromb Haemost. 2012 Jul;108(1):54-64. doi: 10.1160/TH12-01-0023. Epub 2012 May 3. Thromb Haemost. 2012. PMID: 22552265 Clinical Trial.

3

Absence of pharmacodynamic interaction between inclacumab and heparin in healthy smokers.

Schmitt C, Mudie N, Ciorciaro C, Gaudreault J. Schmitt C, et al. J Cardiovasc Pharmacol. 2015 Apr;65(4):386-92. doi: 10.1097/FJC.0000000000000211. J Cardiovasc Pharmacol. 2015. PMID: 25602360

4

First-in-Man Study With Inclacumab, a Human Monoclonal Antibody Against P-selectin.

Schmitt C, Abt M, Ciorciaro C, Kling D, Jamois C, Schick E, Solier C, Benghozi R, Gaudreault J. Schmitt C, et al. J Cardiovasc Pharmacol. 2015 Jun;65(6):611-9. doi: 10.1097/FJC.0000000000000233. J Cardiovasc Pharmacol. 2015. PMID: 25714598 Free PMC article. Clinical Trial.

5

Lack of ethnic differences in the pharmacokinetics and pharmacodynamics of inclacumab in healthy Japanese and Caucasian subjects.

Morrison M, Palermo G, Schmitt C. Morrison M, et al. Among authors: schmitt c. Eur J Clin Pharmacol. 2015 Nov;71(11):1365-74. doi: 10.1007/s00228-015-1938-4. Epub 2015 Sep 12. Eur J Clin Pharmacol. 2015. PMID: 26363899 Clinical Trial.

6

Pharmacokinetics and Pharmacodynamics of Emicizumab in Persons with Hemophilia A with Factor VIII Inhibitors: HAVEN 1 Study.

Schmitt C, Adamkewicz JI, Xu J, Petry C, Catalani O, Young G, Negrier C, Callaghan MU, Levy GG. Schmitt C, et al. Thromb Haemost. 2021 Mar;121(3):351-360. doi: 10.1055/s-0040-1717114. Epub 2020 Oct 21. Thromb Haemost. 2021. PMID: 33086400 Free PMC article. Clinical Trial.

7

Crossover dose escalation study to assess safety, pharmacokinetics, and pharmacodynamics of single doses of R1663, an oral factor Xa inhibitor, in healthy male volunteers.

Schmitt C, Pannier A, McIntyre C, Zandt H, Ciorciaro C, Winters K, Pepper T. Schmitt C, et al. J Clin Pharmacol. 2012 Apr;52(4):499-510. doi: 10.1177/0091270011401621. Epub 2011 May 12. J Clin Pharmacol. 2012. PMID: 21566199 Clinical Trial.

8

Thorough QT/QTc study of tocilizumab after single-dose administration at therapeutic and supratherapeutic doses in healthy subjects.

Grange S, Schmitt C, Banken L, Kuhn B, Zhang X. Grange S, et al. Among authors: schmitt c. Int J Clin Pharmacol Ther. 2011 Nov;49(11):648-55. doi: 10.5414/cp201549. Int J Clin Pharmacol Ther. 2011. PMID: 22011689 Clinical Trial.

9

A Pharmacometric Approach to Substitute for a Conventional Dose-Finding Study in Rare Diseases: Example of Phase III Dose Selection for Emicizumab in Hemophilia A.

Yoneyama K, Schmitt C, Kotani N, Levy GG, Kasai R, Iida S, Shima M, Kawanishi T. Yoneyama K, et al. Among authors: schmitt c. Clin Pharmacokinet. 2018 Sep;57(9):1123-1134. doi: 10.1007/s40262-017-0616-3. Clin Pharmacokinet. 2018. PMID: 29214439 Free PMC article. Clinical Trial.

10

Efficacy, safety, and pharmacokinetics of emicizumab prophylaxis given every 4 weeks in people with haemophilia A (HAVEN 4): a multicentre, open-label, non-randomised phase 3 study.

Pipe SW, Shima M, Lehle M, Shapiro A, Chebon S, Fukutake K, Key NS, Portron A, Schmitt C, Podolak-Dawidziak M, Selak Bienz N, Hermans C, Campinha-Bacote A, Kiialainen A, Peerlinck K, Levy GG, Jiménez-Yuste V. Pipe SW, et al. Among authors: schmitt c. Lancet Haematol. 2019 Jun;6(6):e295-e305. doi: 10.1016/S2352-3026(19)30054-7. Epub 2019 Apr 16. Lancet Haematol. 2019. PMID: 31003963 Clinical Trial.

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