Gao LX - Search Results

1

Astragaloside II triggers T cell activation through regulation of CD45 protein tyrosine phosphatase activity.

Wan CP, Gao LX, Hou LF, Yang XQ, He PL, Yang YF, Tang W, Yue JM, Li J, Zuo JP. Wan CP, et al. Among authors: gao lx. Acta Pharmacol Sin. 2013 Apr;34(4):522-30. doi: 10.1038/aps.2012.208. Epub 2013 Mar 25. Acta Pharmacol Sin. 2013. PMID: 23524573 Free PMC article.

2

A unique and rapid approach toward the efficient development of novel protein tyrosine phosphatase (PTP) inhibitors based on 'clicked' pseudo-glycopeptides.

Yang JW, He XP, Li C, Gao LX, Sheng L, Xie J, Shi XX, Tang Y, Li J, Chen GR. Yang JW, et al. Among authors: gao lx. Bioorg Med Chem Lett. 2011 Feb 15;21(4):1092-6. doi: 10.1016/j.bmcl.2010.12.126. Epub 2010 Dec 31. Bioorg Med Chem Lett. 2011. PMID: 21251827

3

Facile fabrication of promising protein tyrosine phosphatase (PTP) inhibitor entities based on 'clicked' serine/threonine-monosaccharide hybrids.

He XP, Deng Q, Gao LX, Li C, Zhang W, Zhou YB, Tang Y, Shi XX, Xie J, Li J, Chen GR, Chen K. He XP, et al. Among authors: gao lx. Bioorg Med Chem. 2011 Jul 1;19(13):3892-900. doi: 10.1016/j.bmc.2011.05.049. Epub 2011 May 27. Bioorg Med Chem. 2011. PMID: 21665482

4

Discovering the distinct inhibitory effects between C4-epimeric glycosyl amino acids: new insight into the development of protein tyrosine phosphatase inhibitors.

He XP, Li C, Wang ZZ, Gao LX, Shi XX, Tang Y, Xie J, Li J, Chen GR, Chen K. He XP, et al. Among authors: gao lx. Glycoconj J. 2011 Oct;28(7):493-7. doi: 10.1007/s10719-011-9347-0. Epub 2011 Sep 6. Glycoconj J. 2011. PMID: 21894463

5

Synthesis and biological evaluation of 2,4,6-trihydroxychalcone derivatives as novel protein tyrosine phosphatase 1B inhibitors.

Sun LP, Gao LX, Ma WP, Nan FJ, Li J, Piao HR. Sun LP, et al. Among authors: gao lx. Chem Biol Drug Des. 2012 Oct;80(4):584-90. doi: 10.1111/j.1747-0285.2012.01431.x. Epub 2012 Jul 13. Chem Biol Drug Des. 2012. PMID: 22805439

6

Synthesis and characterization of 5,7-dihydroxyflavanone derivatives as novel protein tyrosine phosphatase 1B inhibitors.

Sun LP, Ma WP, Gao LX, Yang LL, Quan YC, Li J, Piao HR. Sun LP, et al. Among authors: gao lx. J Enzyme Inhib Med Chem. 2013 Dec;28(6):1199-204. doi: 10.3109/14756366.2012.723206. Epub 2012 Sep 26. J Enzyme Inhib Med Chem. 2013. PMID: 23009604 Free article.

7

Synthesis and biological evaluation of 4,4-dimethyl lithocholic acid derivatives as novel inhibitors of protein tyrosine phosphatase 1B.

He HB, Gao LX, Deng QF, Ma WP, Tang CL, Qiu WW, Tang J, Li JY, Li J, Yang F. He HB, et al. Among authors: gao lx. Bioorg Med Chem Lett. 2012 Dec 1;22(23):7237-42. doi: 10.1016/j.bmcl.2012.09.040. Epub 2012 Sep 21. Bioorg Med Chem Lett. 2012. PMID: 23067554

8

Discovery of di-indolinone as a novel scaffold for protein tyrosine phosphatase 1B inhibitors.

Dai HL, Gao LX, Yang Y, Li JY, Cheng JG, Li J, Wen R, Peng YQ, Zheng JB. Dai HL, et al. Among authors: gao lx. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7440-3. doi: 10.1016/j.bmcl.2012.10.054. Epub 2012 Oct 17. Bioorg Med Chem Lett. 2012. PMID: 23122522

9

Cembrane diterpenoids from the soft coral Sarcophyton trocheliophorum Marenzeller as a new class of PTP1B inhibitors.

Liang LF, Gao LX, Li J, Taglialatela-Scafati O, Guo YW. Liang LF, et al. Among authors: gao lx. Bioorg Med Chem. 2013 Sep 1;21(17):5076-80. doi: 10.1016/j.bmc.2013.06.043. Epub 2013 Jun 27. Bioorg Med Chem. 2013. PMID: 23859780

10

The first synthesis of natural disulfide bruguiesulfurol and biological evaluation of its derivatives as a novel scaffold for PTP1B inhibitors.

Chen J, Jiang CS, Ma WQ, Gao LX, Gong JX, Li JY, Li J, Guo YW. Chen J, et al. Among authors: gao lx. Bioorg Med Chem Lett. 2013 Sep 15;23(18):5061-5. doi: 10.1016/j.bmcl.2013.07.039. Epub 2013 Jul 25. Bioorg Med Chem Lett. 2013. PMID: 23942421

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