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Page 1
Impact of isolated germline JAK2V617I mutation on human hematopoiesis.
Mead AJ, Chowdhury O, Pecquet C, Dusa A, Woll P, Atkinson D, Burns A, Score J, Rugless M, Clifford R, Moule S, Bienz N, Vyas P, Cross N, Gale RE, Henderson S, Constantinescu SN, Schuh A, Jacobsen SE. Mead AJ, et al. Among authors: constantinescu sn. Blood. 2013 May 16;121(20):4156-65. doi: 10.1182/blood-2012-05-430926. Epub 2013 Mar 27. Blood. 2013. PMID: 23535062 Free article.
JAK2, the JAK2 V617F mutant and cytokine receptors.
Staerk J, Kallin A, Royer Y, Diaconu CC, Dusa A, Demoulin JB, Vainchenker W, Constantinescu SN. Staerk J, et al. Among authors: constantinescu sn. Pathol Biol (Paris). 2007 Mar;55(2):88-91. doi: 10.1016/j.patbio.2006.06.003. Epub 2006 Aug 14. Pathol Biol (Paris). 2007. PMID: 16904848 Review.
The Jak2V617F oncogene associated with myeloproliferative diseases requires a functional FERM domain for transformation and for expression of the Myc and Pim proto-oncogenes.
Wernig G, Gonneville JR, Crowley BJ, Rodrigues MS, Reddy MM, Hudon HE, Walz C, Reiter A, Podar K, Royer Y, Constantinescu SN, Tomasson MH, Griffin JD, Gilliland DG, Sattler M. Wernig G, et al. Among authors: constantinescu sn. Blood. 2008 Apr 1;111(7):3751-9. doi: 10.1182/blood-2007-07-102186. Epub 2008 Jan 23. Blood. 2008. PMID: 18216297 Free PMC article.
Mining for JAK-STAT mutations in cancer.
Constantinescu SN, Girardot M, Pecquet C. Constantinescu SN, et al. Trends Biochem Sci. 2008 Mar;33(3):122-31. doi: 10.1016/j.tibs.2007.12.002. Trends Biochem Sci. 2008. PMID: 18291658 Review.
Induction of myeloproliferative disorder and myelofibrosis by thrombopoietin receptor W515 mutants is mediated by cytosolic tyrosine 112 of the receptor.
Pecquet C, Staerk J, Chaligné R, Goss V, Lee KA, Zhang X, Rush J, Van Hees J, Poirel HA, Scheiff JM, Vainchenker W, Giraudier S, Polakiewicz RD, Constantinescu SN. Pecquet C, et al. Among authors: constantinescu sn. Blood. 2010 Feb 4;115(5):1037-48. doi: 10.1182/blood-2008-10-183558. Epub 2009 Dec 8. Blood. 2010. PMID: 19996410 Free article.
220 results