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Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling.
Furtado MB, Wilmanns JC, Chandran A, Perera J, Hon O, Biben C, Willow TJ, Nim HT, Kaur G, Simonds S, Wu Q, Willians D, Salimova E, Plachta N, Denegre JM, Murray SA, Fatkin D, Cowley M, Pearson JT, Kaye D, Ramialison M, Harvey RP, Rosenthal NA, Costa MW. Furtado MB, et al. Among authors: costa mw. JCI Insight. 2017 Mar 23;2(6):e88271. doi: 10.1172/jci.insight.88271. JCI Insight. 2017. PMID: 28352650 Free PMC article.
NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network.
Anderson DJ, Kaplan DI, Bell KM, Koutsis K, Haynes JM, Mills RJ, Phelan DG, Qian EL, Leitoguinho AR, Arasaratnam D, Labonne T, Ng ES, Davis RP, Casini S, Passier R, Hudson JE, Porrello ER, Costa MW, Rafii A, Curl CL, Delbridge LM, Harvey RP, Oshlack A, Cheung MM, Mummery CL, Petrou S, Elefanty AG, Stanley EG, Elliott DA. Anderson DJ, et al. Among authors: costa mw. Nat Commun. 2018 Apr 10;9(1):1373. doi: 10.1038/s41467-018-03714-x. Nat Commun. 2018. PMID: 29636455 Free PMC article.
3D-cardiomics: A spatial transcriptional atlas of the mammalian heart.
Mohenska M, Tan NM, Tokolyi A, Furtado MB, Costa MW, Perry AJ, Hatwell-Humble J, van Duijvenboden K, Nim HT, Ji YMM, Charitakis N, Bienroth D, Bolk F, Vivien C, Knaupp AS, Powell DR, Elliott DA, Porrello ER, Nilsson SK, Del Monte-Nieto G, Rosenthal NA, Rossello FJ, Polo JM, Ramialison M. Mohenska M, et al. Among authors: costa mw. J Mol Cell Cardiol. 2022 Feb;163:20-32. doi: 10.1016/j.yjmcc.2021.09.011. Epub 2021 Oct 5. J Mol Cell Cardiol. 2022. PMID: 34624332
Complex SUMO-1 regulation of cardiac transcription factor Nkx2-5.
Costa MW, Lee S, Furtado MB, Xin L, Sparrow DB, Martinez CG, Dunwoodie SL, Kurtenbach E, Mohun T, Rosenthal N, Harvey RP. Costa MW, et al. PLoS One. 2011;6(9):e24812. doi: 10.1371/journal.pone.0024812. Epub 2011 Sep 12. PLoS One. 2011. PMID: 21931855 Free PMC article.
Cardiogenic genes expressed in cardiac fibroblasts contribute to heart development and repair.
Furtado MB, Costa MW, Pranoto EA, Salimova E, Pinto AR, Lam NT, Park A, Snider P, Chandran A, Harvey RP, Boyd R, Conway SJ, Pearson J, Kaye DM, Rosenthal NA. Furtado MB, et al. Among authors: costa mw. Circ Res. 2014 Apr 25;114(9):1422-34. doi: 10.1161/CIRCRESAHA.114.302530. Epub 2014 Mar 20. Circ Res. 2014. PMID: 24650916 Free PMC article.
CARFMAP: A Curated Pathway Map of Cardiac Fibroblasts.
Nim HT, Furtado MB, Costa MW, Kitano H, Rosenthal NA, Boyd SE. Nim HT, et al. Among authors: costa mw. PLoS One. 2015 Dec 16;10(12):e0143274. doi: 10.1371/journal.pone.0143274. eCollection 2015. PLoS One. 2015. PMID: 26673252 Free PMC article.
42 results