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4-IBP, a sigma1 receptor agonist, decreases the migration of human cancer cells, including glioblastoma cells, in vitro and sensitizes them in vitro and in vivo to cytotoxic insults of proapoptotic and proautophagic drugs.
Mégalizzi V, Mathieu V, Mijatovic T, Gailly P, Debeir O, De Neve N, Van Damme M, Bontempi G, Haibe-Kains B, Decaestecker C, Kondo Y, Kiss R, Lefranc F. Mégalizzi V, et al. Among authors: kiss r. Neoplasia. 2007 May;9(5):358-69. doi: 10.1593/neo.07130. Neoplasia. 2007. PMID: 17534441 Free PMC article.
Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
Lamoral-Theys D, Andolfi A, Van Goietsenoven G, Cimmino A, Le Calvé B, Wauthoz N, Mégalizzi V, Gras T, Bruyère C, Dubois J, Mathieu V, Kornienko A, Kiss R, Evidente A. Lamoral-Theys D, et al. Among authors: kiss r. J Med Chem. 2009 Oct 22;52(20):6244-56. doi: 10.1021/jm901031h. J Med Chem. 2009. PMID: 19788245 Free PMC article.
Trivanillic polyphenols with anticancer cytostatic effects through the targeting of multiple kinases and intracellular Ca2+ release.
Lamoral-Theys D, Wauthoz N, Heffeter P, Mathieu V, Jungwirth U, Lefranc F, Nève J, Dubois J, Dufrasne F, Amighi K, Berger W, Gailly P, Kiss R. Lamoral-Theys D, et al. Among authors: kiss r. J Cell Mol Med. 2012 Jul;16(7):1421-34. doi: 10.1111/j.1582-4934.2011.01403.x. J Cell Mol Med. 2012. PMID: 21810170 Free PMC article.
Ophiobolin A, a sesterterpenoid fungal phytotoxin, displays higher in vitro growth-inhibitory effects in mammalian than in plant cells and displays in vivo antitumor activity.
Bury M, Novo-Uzal E, Andolfi A, Cimini S, Wauthoz N, Heffeter P, Lallemand B, Avolio F, Delporte C, Cimmino A, Dubois J, Van Antwerpen P, Zonno MC, Vurro M, Poumay Y, Berger W, Evidente A, De Gara L, Kiss R, Locato V. Bury M, et al. Among authors: kiss r. Int J Oncol. 2013 Aug;43(2):575-85. doi: 10.3892/ijo.2013.1979. Epub 2013 Jun 10. Int J Oncol. 2013. PMID: 23754298
Sphaeropsidin A shows promising activity against drug-resistant cancer cells by targeting regulatory volume increase.
Mathieu V, Chantôme A, Lefranc F, Cimmino A, Miklos W, Paulitschke V, Mohr T, Maddau L, Kornienko A, Berger W, Vandier C, Evidente A, Delpire E, Kiss R. Mathieu V, et al. Among authors: kiss r. Cell Mol Life Sci. 2015 Oct;72(19):3731-46. doi: 10.1007/s00018-015-1902-6. Epub 2015 Apr 14. Cell Mol Life Sci. 2015. PMID: 25868554 Free PMC article.
1,013 results