Ren J - Search Results

1

Rational engineering of recombinant picornavirus capsids to produce safe, protective vaccine antigen.

Porta C, Kotecha A, Burman A, Jackson T, Ren J, Loureiro S, Jones IM, Fry EE, Stuart DI, Charleston B. Porta C, et al. Among authors: ren j. PLoS Pathog. 2013 Mar;9(3):e1003255. doi: 10.1371/journal.ppat.1003255. Epub 2013 Mar 27. PLoS Pathog. 2013. PMID: 23544011 Free PMC article.

2

The N-glycosidase mechanism of ribosome-inactivating proteins implied by crystal structures of alpha-momorcharin.

Ren J, Wang Y, Dong Y, Stuart DI. Ren J, et al. Structure. 1994 Jan 15;2(1):7-16. doi: 10.1016/s0969-2126(00)00004-6. Structure. 1994. PMID: 8075985

3

Alpha-lactalbumin possesses a distinct zinc binding site.

Ren J, Stuart DI, Acharya KR. Ren J, et al. J Biol Chem. 1993 Sep 15;268(26):19292-8. J Biol Chem. 1993. PMID: 8366079 Free article.

4

Unique features in the structure of the complex between HIV-1 reverse transcriptase and the bis(heteroaryl)piperazine (BHAP) U-90152 explain resistance mutations for this nonnucleoside inhibitor.

Esnouf RM, Ren J, Hopkins AL, Ross CK, Jones EY, Stammers DK, Stuart DI. Esnouf RM, et al. Among authors: ren j. Proc Natl Acad Sci U S A. 1997 Apr 15;94(8):3984-9. doi: 10.1073/pnas.94.8.3984. Proc Natl Acad Sci U S A. 1997. PMID: 9108091 Free PMC article.

5

3'-Azido-3'-deoxythymidine drug resistance mutations in HIV-1 reverse transcriptase can induce long range conformational changes.

Ren J, Esnouf RM, Hopkins AL, Jones EY, Kirby I, Keeling J, Ross CK, Larder BA, Stuart DI, Stammers DK. Ren J, et al. Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9518-23. doi: 10.1073/pnas.95.16.9518. Proc Natl Acad Sci U S A. 1998. PMID: 9689112 Free PMC article.

6

Binding of the second generation non-nucleoside inhibitor S-1153 to HIV-1 reverse transcriptase involves extensive main chain hydrogen bonding.

Ren J, Nichols C, Bird LE, Fujiwara T, Sugimoto H, Stuart DI, Stammers DK. Ren J, et al. J Biol Chem. 2000 May 12;275(19):14316-20. doi: 10.1074/jbc.275.19.14316. J Biol Chem. 2000. PMID: 10799511 Free article.

7

Structural basis for the resilience of efavirenz (DMP-266) to drug resistance mutations in HIV-1 reverse transcriptase.

Ren J, Milton J, Weaver KL, Short SA, Stuart DI, Stammers DK. Ren J, et al. Structure. 2000 Oct 15;8(10):1089-94. doi: 10.1016/s0969-2126(00)00513-x. Structure. 2000. PMID: 11080630 Free article.

8

Crystal structures of Zidovudine- or Lamivudine-resistant human immunodeficiency virus type 1 reverse transcriptases containing mutations at codons 41, 184, and 215.

Chamberlain PP, Ren J, Nichols CE, Douglas L, Lennerstrand J, Larder BA, Stuart DI, Stammers DK. Chamberlain PP, et al. Among authors: ren j. J Virol. 2002 Oct;76(19):10015-9. doi: 10.1128/jvi.76.19.10015-10019.2002. J Virol. 2002. PMID: 12208978 Free PMC article.

9

Structure of HIV-2 reverse transcriptase at 2.35-A resolution and the mechanism of resistance to non-nucleoside inhibitors.

Ren J, Bird LE, Chamberlain PP, Stewart-Jones GB, Stuart DI, Stammers DK. Ren J, et al. Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14410-5. doi: 10.1073/pnas.222366699. Epub 2002 Oct 17. Proc Natl Acad Sci U S A. 2002. PMID: 12386343 Free PMC article.

10

Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1.

Hopkins AL, Ren J, Milton J, Hazen RJ, Chan JH, Stuart DI, Stammers DK. Hopkins AL, et al. Among authors: ren j. J Med Chem. 2004 Nov 18;47(24):5912-22. doi: 10.1021/jm040071z. J Med Chem. 2004. PMID: 15537346

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