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The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib.
Hantschel O, Rix U, Schmidt U, Bürckstümmer T, Kneidinger M, Schütze G, Colinge J, Bennett KL, Ellmeier W, Valent P, Superti-Furga G. Hantschel O, et al. Among authors: ellmeier w. Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13283-8. doi: 10.1073/pnas.0702654104. Epub 2007 Aug 7. Proc Natl Acad Sci U S A. 2007. PMID: 17684099 Free PMC article.
The protein tyrosine kinase Tec regulates mast cell function.
Schmidt U, Abramova A, Boucheron N, Eckelhart E, Schebesta A, Bilic I, Kneidinger M, Unger B, Hammer M, Sibilia M, Valent P, Ellmeier W. Schmidt U, et al. Among authors: ellmeier w. Eur J Immunol. 2009 Nov;39(11):3228-38. doi: 10.1002/eji.200838839. Eur J Immunol. 2009. PMID: 19688741 Free article.
The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset.
Boucheron N, Sharif O, Schebesta A, Croxford A, Raberger J, Schmidt U, Vigl B, Bauer J, Bankoti R, Lassmann H, Epstein MM, Knapp S, Waisman A, Ellmeier W. Boucheron N, et al. Among authors: ellmeier w. J Immunol. 2010 Nov 1;185(9):5111-9. doi: 10.4049/jimmunol.1001734. Epub 2010 Sep 24. J Immunol. 2010. PMID: 20870948
Cross-talk between interferon-γ and hedgehog signaling regulates adipogenesis.
Todoric J, Strobl B, Jais A, Boucheron N, Bayer M, Amann S, Lindroos J, Teperino R, Prager G, Bilban M, Ellmeier W, Krempler F, Müller M, Wagner O, Patsch W, Pospisilik JA, Esterbauer H. Todoric J, et al. Among authors: ellmeier w. Diabetes. 2011 Jun;60(6):1668-76. doi: 10.2337/db10-1628. Epub 2011 May 2. Diabetes. 2011. PMID: 21536945 Free PMC article.
Btk is a positive regulator in the TREM-1/DAP12 signaling pathway.
Ormsby T, Schlecker E, Ferdin J, Tessarz AS, Angelisová P, Köprülü AD, Borte M, Warnatz K, Schulze I, Ellmeier W, Horejsí V, Cerwenka A. Ormsby T, et al. Among authors: ellmeier w. Blood. 2011 Jul 28;118(4):936-45. doi: 10.1182/blood-2010-11-317016. Epub 2011 Jun 9. Blood. 2011. PMID: 21659545 Free article.
HDAC1 controls CD8+ T cell homeostasis and antiviral response.
Tschismarov R, Firner S, Gil-Cruz C, Göschl L, Boucheron N, Steiner G, Matthias P, Seiser C, Ludewig B, Ellmeier W. Tschismarov R, et al. Among authors: ellmeier w. PLoS One. 2014 Oct 21;9(10):e110576. doi: 10.1371/journal.pone.0110576. eCollection 2014. PLoS One. 2014. PMID: 25333902 Free PMC article.
96 results