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Three groups in the 28 joints for rheumatoid arthritis synovitis--analysis using more than 17,000 assessments in the KURAMA database.
Terao C, Hashimoto M, Yamamoto K, Murakami K, Ohmura K, Nakashima R, Yamakawa N, Yoshifuji H, Yukawa N, Kawabata D, Usui T, Yoshitomi H, Furu M, Yamada R, Matsuda F, Ito H, Fujii T, Mimori T. Terao C, et al. Among authors: hashimoto m. PLoS One. 2013;8(3):e59341. doi: 10.1371/journal.pone.0059341. Epub 2013 Mar 12. PLoS One. 2013. PMID: 23555018 Free PMC article.
Gamma/delta T cells are the predominant source of interleukin-17 in affected joints in collagen-induced arthritis, but not in rheumatoid arthritis.
Ito Y, Usui T, Kobayashi S, Iguchi-Hashimoto M, Ito H, Yoshitomi H, Nakamura T, Shimizu M, Kawabata D, Yukawa N, Hashimoto M, Sakaguchi N, Sakaguchi S, Yoshifuji H, Nojima T, Ohmura K, Fujii T, Mimori T. Ito Y, et al. Among authors: hashimoto m. Arthritis Rheum. 2009 Aug;60(8):2294-303. doi: 10.1002/art.24687. Arthritis Rheum. 2009. PMID: 19644886 Free article.
Complement drives Th17 cell differentiation and triggers autoimmune arthritis.
Hashimoto M, Hirota K, Yoshitomi H, Maeda S, Teradaira S, Akizuki S, Prieto-Martin P, Nomura T, Sakaguchi N, Köhl J, Heyman B, Takahashi M, Fujita T, Mimori T, Sakaguchi S. Hashimoto M, et al. J Exp Med. 2010 Jun 7;207(6):1135-43. doi: 10.1084/jem.20092301. Epub 2010 May 10. J Exp Med. 2010. PMID: 20457757 Free PMC article.
4,702 results