Miggiano R - Search Results

1

Biochemical and structural studies of the Mycobacterium tuberculosis O6-methylguanine methyltransferase and mutated variants.

Miggiano R, Casazza V, Garavaglia S, Ciaramella M, Perugino G, Rizzi M, Rossi F. Miggiano R, et al. J Bacteriol. 2013 Jun;195(12):2728-36. doi: 10.1128/JB.02298-12. Epub 2013 Apr 5. J Bacteriol. 2013. PMID: 23564173 Free PMC article.

2

Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein.

Perugino G, Miggiano R, Serpe M, Vettone A, Valenti A, Lahiri S, Rossi F, Rossi M, Rizzi M, Ciaramella M. Perugino G, et al. Among authors: miggiano r. Nucleic Acids Res. 2015 Oct 15;43(18):8801-16. doi: 10.1093/nar/gkv774. Epub 2015 Jul 30. Nucleic Acids Res. 2015. PMID: 26227971 Free PMC article.

3

Crystal structure of Mycobacterium tuberculosis O6-methylguanine-DNA methyltransferase protein clusters assembled on to damaged DNA.

Miggiano R, Perugino G, Ciaramella M, Serpe M, Rejman D, Páv O, Pohl R, Garavaglia S, Lahiri S, Rizzi M, Rossi F. Miggiano R, et al. Biochem J. 2016 Jan 15;473(2):123-33. doi: 10.1042/BJ20150833. Epub 2015 Oct 28. Biochem J. 2016. PMID: 26512127

4

Interdomain interactions rearrangements control the reaction steps of a thermostable DNA alkyltransferase.

Morrone C, Miggiano R, Serpe M, Massarotti A, Valenti A, Del Monaco G, Rossi M, Rossi F, Rizzi M, Perugino G, Ciaramella M. Morrone C, et al. Among authors: miggiano r. Biochim Biophys Acta Gen Subj. 2017 Feb;1861(2):86-96. doi: 10.1016/j.bbagen.2016.10.020. Epub 2016 Oct 22. Biochim Biophys Acta Gen Subj. 2017. PMID: 27777086

5

Biochemical and structural investigations on phosphoribosylpyrophosphate synthetase from Mycobacterium smegmatis.

Donini S, Garavaglia S, Ferraris DM, Miggiano R, Mori S, Shibayama K, Rizzi M. Donini S, et al. Among authors: miggiano r. PLoS One. 2017 Apr 18;12(4):e0175815. doi: 10.1371/journal.pone.0175815. eCollection 2017. PLoS One. 2017. PMID: 28419153 Free PMC article.

6

Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis.

Donini S, Ferraris DM, Miggiano R, Massarotti A, Rizzi M. Donini S, et al. Among authors: miggiano r. Sci Rep. 2017 Apr 26;7(1):1180. doi: 10.1038/s41598-017-01057-z. Sci Rep. 2017. PMID: 28446777 Free PMC article.

7

Mycobacterium tuberculosis UvrB forms dimers in solution and interacts with UvrA in the absence of ligands.

Lahiri S, Rizzi M, Rossi F, Miggiano R. Lahiri S, et al. Among authors: miggiano r. Proteins. 2018 Jan;86(1):98-109. doi: 10.1002/prot.25412. Epub 2017 Nov 11. Proteins. 2018. PMID: 29082541

8

Every OGT Is Illuminated … by Fluorescent and Synchrotron Lights.

Miggiano R, Valenti A, Rossi F, Rizzi M, Perugino G, Ciaramella M. Miggiano R, et al. Int J Mol Sci. 2017 Dec 5;18(12):2613. doi: 10.3390/ijms18122613. Int J Mol Sci. 2017. PMID: 29206193 Free PMC article. Review.

9

Mycobacterium tuberculosis Molecular Determinants of Infection, Survival Strategies, and Vulnerable Targets.

Ferraris DM, Miggiano R, Rossi F, Rizzi M. Ferraris DM, et al. Among authors: miggiano r. Pathogens. 2018 Feb 1;7(1):17. doi: 10.3390/pathogens7010017. Pathogens. 2018. PMID: 29389854 Free PMC article. Review.

10

Crystal structure of a thermophilic O⁶-alkylguanine-DNA alkyltransferase-derived self-labeling protein-tag in covalent complex with a fluorescent probe.

Rossi F, Morrone C, Massarotti A, Ferraris DM, Valenti A, Perugino G, Miggiano R. Rossi F, et al. Among authors: miggiano r. Biochem Biophys Res Commun. 2018 Jun 7;500(3):698-703. doi: 10.1016/j.bbrc.2018.04.139. Epub 2018 Apr 30. Biochem Biophys Res Commun. 2018. PMID: 29684348

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