Perugino G - Search Results

1

Biochemical and structural studies of the Mycobacterium tuberculosis O6-methylguanine methyltransferase and mutated variants.

Miggiano R, Casazza V, Garavaglia S, Ciaramella M, Perugino G, Rizzi M, Rossi F. Miggiano R, et al. Among authors: perugino g. J Bacteriol. 2013 Jun;195(12):2728-36. doi: 10.1128/JB.02298-12. Epub 2013 Apr 5. J Bacteriol. 2013. PMID: 23564173 Free PMC article.

2

Crystal structure of Mycobacterium tuberculosis O6-methylguanine-DNA methyltransferase protein clusters assembled on to damaged DNA.

Miggiano R, Perugino G, Ciaramella M, Serpe M, Rejman D, Páv O, Pohl R, Garavaglia S, Lahiri S, Rizzi M, Rossi F. Miggiano R, et al. Among authors: perugino g. Biochem J. 2016 Jan 15;473(2):123-33. doi: 10.1042/BJ20150833. Epub 2015 Oct 28. Biochem J. 2016. PMID: 26512127

3

Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein.

Perugino G, Miggiano R, Serpe M, Vettone A, Valenti A, Lahiri S, Rossi F, Rossi M, Rizzi M, Ciaramella M. Perugino G, et al. Nucleic Acids Res. 2015 Oct 15;43(18):8801-16. doi: 10.1093/nar/gkv774. Epub 2015 Jul 30. Nucleic Acids Res. 2015. PMID: 26227971 Free PMC article.

4

Interdomain interactions rearrangements control the reaction steps of a thermostable DNA alkyltransferase.

Morrone C, Miggiano R, Serpe M, Massarotti A, Valenti A, Del Monaco G, Rossi M, Rossi F, Rizzi M, Perugino G, Ciaramella M. Morrone C, et al. Among authors: perugino g. Biochim Biophys Acta Gen Subj. 2017 Feb;1861(2):86-96. doi: 10.1016/j.bbagen.2016.10.020. Epub 2016 Oct 22. Biochim Biophys Acta Gen Subj. 2017. PMID: 27777086

5

Every OGT Is Illuminated … by Fluorescent and Synchrotron Lights.

Miggiano R, Valenti A, Rossi F, Rizzi M, Perugino G, Ciaramella M. Miggiano R, et al. Among authors: perugino g. Int J Mol Sci. 2017 Dec 5;18(12):2613. doi: 10.3390/ijms18122613. Int J Mol Sci. 2017. PMID: 29206193 Free PMC article. Review.

6

Crystal structure of a thermophilic O⁶-alkylguanine-DNA alkyltransferase-derived self-labeling protein-tag in covalent complex with a fluorescent probe.

Rossi F, Morrone C, Massarotti A, Ferraris DM, Valenti A, Perugino G, Miggiano R. Rossi F, et al. Among authors: perugino g. Biochem Biophys Res Commun. 2018 Jun 7;500(3):698-703. doi: 10.1016/j.bbrc.2018.04.139. Epub 2018 Apr 30. Biochem Biophys Res Commun. 2018. PMID: 29684348

7

O⁶-alkylguanine-DNA Alkyltransferases in Microbes Living on the Edge: From Stability to Applicability.

Mattossovich R, Merlo R, Miggiano R, Valenti A, Perugino G. Mattossovich R, et al. Among authors: perugino g. Int J Mol Sci. 2020 Apr 20;21(8):2878. doi: 10.3390/ijms21082878. Int J Mol Sci. 2020. PMID: 32326075 Free PMC article. Review.

8

The DNA Alkylguanine DNA Alkyltransferase-2 (AGT-2) Of Caenorhabditis Elegans Is Involved In Meiosis And Early Development Under Physiological Conditions.

Serpe M, Forenza C, Adamo A, Russo N, Perugino G, Ciaramella M, Valenti A. Serpe M, et al. Among authors: perugino g. Sci Rep. 2019 May 3;9(1):6889. doi: 10.1038/s41598-019-43394-1. Sci Rep. 2019. PMID: 31053748 Free PMC article.

9

The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate.

Merlo R, Caprioglio D, Cillo M, Valenti A, Mattossovich R, Morrone C, Massarotti A, Rossi F, Miggiano R, Leonardi A, Minassi A, Perugino G. Merlo R, et al. Among authors: perugino g. J Enzyme Inhib Med Chem. 2021 Dec;36(1):85-97. doi: 10.1080/14756366.2020.1841182. J Enzyme Inhib Med Chem. 2021. PMID: 33121288 Free PMC article.

10

First thermostable CLIP-tag by rational design applied to an archaeal O⁶ -alkyl-guanine-DNA-alkyl-transferase.

Merlo R, Mattossovich R, Genta M, Valenti A, Di Mauro G, Minassi A, Miggiano R, Perugino G. Merlo R, et al. Among authors: perugino g. Comput Struct Biotechnol J. 2022 Sep 18;20:5275-5286. doi: 10.1016/j.csbj.2022.09.015. eCollection 2022. Comput Struct Biotechnol J. 2022. PMID: 36212535 Free PMC article.

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