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NADPH oxidase 1 plays a key role in diabetes mellitus-accelerated atherosclerosis.
Gray SP, Di Marco E, Okabe J, Szyndralewiez C, Heitz F, Montezano AC, de Haan JB, Koulis C, El-Osta A, Andrews KL, Chin-Dusting JP, Touyz RM, Wingler K, Cooper ME, Schmidt HH, Jandeleit-Dahm KA. Gray SP, et al. Among authors: szyndralewiez c. Circulation. 2013 May 7;127(18):1888-902. doi: 10.1161/CIRCULATIONAHA.112.132159. Epub 2013 Apr 5. Circulation. 2013. PMID: 23564668
Critical role of Nox4-based NADPH oxidase in glucose-induced oxidative stress in the kidney: implications in type 2 diabetic nephropathy.
Sedeek M, Callera G, Montezano A, Gutsol A, Heitz F, Szyndralewiez C, Page P, Kennedy CR, Burns KD, Touyz RM, Hébert RL. Sedeek M, et al. Among authors: szyndralewiez c. Am J Physiol Renal Physiol. 2010 Dec;299(6):F1348-58. doi: 10.1152/ajprenal.00028.2010. Epub 2010 Jul 14. Am J Physiol Renal Physiol. 2010. PMID: 20630933 Free article.
Renoprotective effects of a novel Nox1/4 inhibitor in a mouse model of Type 2 diabetes.
Sedeek M, Gutsol A, Montezano AC, Burger D, Nguyen Dinh Cat A, Kennedy CR, Burns KD, Cooper ME, Jandeleit-Dahm K, Page P, Szyndralewiez C, Heitz F, Hebert RL, Touyz RM. Sedeek M, et al. Among authors: szyndralewiez c. Clin Sci (Lond). 2013 Feb;124(3):191-202. doi: 10.1042/CS20120330. Clin Sci (Lond). 2013. PMID: 22920224
NADPH oxidase, NOX1, mediates vascular injury in ischemic retinopathy.
Wilkinson-Berka JL, Deliyanti D, Rana I, Miller AG, Agrotis A, Armani R, Szyndralewiez C, Wingler K, Touyz RM, Cooper ME, Jandeleit-Dahm KA, Schmidt HH. Wilkinson-Berka JL, et al. Among authors: szyndralewiez c. Antioxid Redox Signal. 2014 Jun 10;20(17):2726-40. doi: 10.1089/ars.2013.5357. Epub 2013 Oct 30. Antioxid Redox Signal. 2014. PMID: 24053718 Free PMC article.
Genetic targeting or pharmacologic inhibition of NADPH oxidase nox4 provides renoprotection in long-term diabetic nephropathy.
Jha JC, Gray SP, Barit D, Okabe J, El-Osta A, Namikoshi T, Thallas-Bonke V, Wingler K, Szyndralewiez C, Heitz F, Touyz RM, Cooper ME, Schmidt HH, Jandeleit-Dahm KA. Jha JC, et al. Among authors: szyndralewiez c. J Am Soc Nephrol. 2014 Jun;25(6):1237-54. doi: 10.1681/ASN.2013070810. Epub 2014 Feb 7. J Am Soc Nephrol. 2014. PMID: 24511132 Free PMC article.
Therapeutic potential of NADPH oxidase 1/4 inhibitors.
Teixeira G, Szyndralewiez C, Molango S, Carnesecchi S, Heitz F, Wiesel P, Wood JM. Teixeira G, et al. Among authors: szyndralewiez c. Br J Pharmacol. 2017 Jun;174(12):1647-1669. doi: 10.1111/bph.13532. Epub 2016 Jul 14. Br J Pharmacol. 2017. PMID: 27273790 Free PMC article. Review.
30 results