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Cardiomyocyte lipids impair β-adrenergic receptor function via PKC activation.
Drosatos K, Bharadwaj KG, Lymperopoulos A, Ikeda S, Khan R, Hu Y, Agarwal R, Yu S, Jiang H, Steinberg SF, Blaner WS, Koch WJ, Goldberg IJ. Drosatos K, et al. Among authors: yu s. Am J Physiol Endocrinol Metab. 2011 Mar;300(3):E489-99. doi: 10.1152/ajpendo.00569.2010. Epub 2010 Dec 7. Am J Physiol Endocrinol Metab. 2011. PMID: 21139071 Free PMC article.
Adipose tissue inflammation and adiponectin resistance in patients with advanced heart failure: correction after ventricular assist device implantation.
Khan RS, Kato TS, Chokshi A, Chew M, Yu S, Wu C, Singh P, Cheema FH, Takayama H, Harris C, Reyes-Soffer G, Knöll R, Milting H, Naka Y, Mancini D, Schulze PC. Khan RS, et al. Among authors: yu s. Circ Heart Fail. 2012 May 1;5(3):340-8. doi: 10.1161/CIRCHEARTFAILURE.111.964031. Epub 2012 Feb 29. Circ Heart Fail. 2012. PMID: 22379072 Free PMC article.
Ventricular assist device implantation corrects myocardial lipotoxicity, reverses insulin resistance, and normalizes cardiac metabolism in patients with advanced heart failure.
Chokshi A, Drosatos K, Cheema FH, Ji R, Khawaja T, Yu S, Kato T, Khan R, Takayama H, Knöll R, Milting H, Chung CS, Jorde U, Naka Y, Mancini DM, Goldberg IJ, Schulze PC. Chokshi A, et al. Among authors: yu s. Circulation. 2012 Jun 12;125(23):2844-53. doi: 10.1161/CIRCULATIONAHA.111.060889. Epub 2012 May 14. Circulation. 2012. PMID: 22586279 Free PMC article.
Rescue of heart lipoprotein lipase-knockout mice confirms a role for triglyceride in optimal heart metabolism and function.
Khan RS, Lin Y, Hu Y, Son NH, Bharadwaj KG, Palacios C, Chokshi A, Ji R, Yu S, Homma S, Schulze PC, Tian R, Goldberg IJ. Khan RS, et al. Among authors: yu s. Am J Physiol Endocrinol Metab. 2013 Dec 1;305(11):E1339-47. doi: 10.1152/ajpendo.00349.2013. Epub 2013 Oct 1. Am J Physiol Endocrinol Metab. 2013. PMID: 24085031 Free PMC article.
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