Fitzgerald KA - Search Results

1

Mouse, but not human STING, binds and signals in response to the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid.

Conlon J, Burdette DL, Sharma S, Bhat N, Thompson M, Jiang Z, Rathinam VA, Monks B, Jin T, Xiao TS, Vogel SN, Vance RE, Fitzgerald KA. Conlon J, et al. Among authors: fitzgerald ka. J Immunol. 2013 May 15;190(10):5216-25. doi: 10.4049/jimmunol.1300097. Epub 2013 Apr 12. J Immunol. 2013. PMID: 23585680 Free PMC article.

2

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.

Fitzgerald KA, McWhirter SM, Faia KL, Rowe DC, Latz E, Golenbock DT, Coyle AJ, Liao SM, Maniatis T. Fitzgerald KA, et al. Nat Immunol. 2003 May;4(5):491-6. doi: 10.1038/ni921. Nat Immunol. 2003. PMID: 12692549

3

LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.

Fitzgerald KA, Rowe DC, Barnes BJ, Caffrey DR, Visintin A, Latz E, Monks B, Pitha PM, Golenbock DT. Fitzgerald KA, et al. J Exp Med. 2003 Oct 6;198(7):1043-55. doi: 10.1084/jem.20031023. Epub 2003 Sep 29. J Exp Med. 2003. PMID: 14517278 Free PMC article.

4

TLR9 signals after translocating from the ER to CpG DNA in the lysosome.

Latz E, Schoenemeyer A, Visintin A, Fitzgerald KA, Monks BG, Knetter CF, Lien E, Nilsen NJ, Espevik T, Golenbock DT. Latz E, et al. Among authors: fitzgerald ka. Nat Immunol. 2004 Feb;5(2):190-8. doi: 10.1038/ni1028. Epub 2004 Jan 11. Nat Immunol. 2004. PMID: 14716310

5

TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression.

Vogel SN, Fitzgerald KA, Fenton MJ. Vogel SN, et al. Among authors: fitzgerald ka. Mol Interv. 2003 Dec;3(8):466-77. doi: 10.1124/mi.3.8.466. Mol Interv. 2003. PMID: 14993454 Review.

6

Specific inhibition of MyD88-independent signaling pathways of TLR3 and TLR4 by resveratrol: molecular targets are TBK1 and RIP1 in TRIF complex.

Youn HS, Lee JY, Fitzgerald KA, Young HA, Akira S, Hwang DH. Youn HS, et al. Among authors: fitzgerald ka. J Immunol. 2005 Sep 1;175(5):3339-46. doi: 10.4049/jimmunol.175.5.3339. J Immunol. 2005. PMID: 16116226

7

The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I.

Rothenfusser S, Goutagny N, DiPerna G, Gong M, Monks BG, Schoenemeyer A, Yamamoto M, Akira S, Fitzgerald KA. Rothenfusser S, et al. Among authors: fitzgerald ka. J Immunol. 2005 Oct 15;175(8):5260-8. doi: 10.4049/jimmunol.175.8.5260. J Immunol. 2005. PMID: 16210631

8

The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction.

Rowe DC, McGettrick AF, Latz E, Monks BG, Gay NJ, Yamamoto M, Akira S, O'Neill LA, Fitzgerald KA, Golenbock DT. Rowe DC, et al. Among authors: fitzgerald ka. Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6299-304. doi: 10.1073/pnas.0510041103. Epub 2006 Apr 7. Proc Natl Acad Sci U S A. 2006. PMID: 16603631 Free PMC article.

9

Role of MyD88 in route-dependent susceptibility to vesicular stomatitis virus infection.

Zhou S, Kurt-Jones EA, Fitzgerald KA, Wang JP, Cerny AM, Chan M, Finberg RW. Zhou S, et al. Among authors: fitzgerald ka. J Immunol. 2007 Apr 15;178(8):5173-81. doi: 10.4049/jimmunol.178.8.5173. J Immunol. 2007. PMID: 17404300

10

The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis.

Roberts ZJ, Goutagny N, Perera PY, Kato H, Kumar H, Kawai T, Akira S, Savan R, van Echo D, Fitzgerald KA, Young HA, Ching LM, Vogel SN. Roberts ZJ, et al. Among authors: fitzgerald ka. J Exp Med. 2007 Jul 9;204(7):1559-69. doi: 10.1084/jem.20061845. Epub 2007 Jun 11. J Exp Med. 2007. PMID: 17562815 Free PMC article.

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