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Epigenetic upregulation of lncRNAs at 13q14.3 in leukemia is linked to the In Cis downregulation of a gene cluster that targets NF-kB.
Garding A, Bhattacharya N, Claus R, Ruppel M, Tschuch C, Filarsky K, Idler I, Zucknick M, Caudron-Herger M, Oakes C, Fleig V, Keklikoglou I, Allegra D, Serra L, Thakurela S, Tiwari V, Weichenhan D, Benner A, Radlwimmer B, Zentgraf H, Wiemann S, Rippe K, Plass C, Döhner H, Lichter P, Stilgenbauer S, Mertens D. Garding A, et al. Among authors: zentgraf h. PLoS Genet. 2013 Apr;9(4):e1003373. doi: 10.1371/journal.pgen.1003373. Epub 2013 Apr 4. PLoS Genet. 2013. PMID: 23593011 Free PMC article.
The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration.
Gdynia G, Sauer SW, Kopitz J, Fuchs D, Duglova K, Ruppert T, Miller M, Pahl J, Cerwenka A, Enders M, Mairbäurl H, Kamiński MM, Penzel R, Zhang C, Fuller JC, Wade RC, Benner A, Chang-Claude J, Brenner H, Hoffmeister M, Zentgraf H, Schirmacher P, Roth W. Gdynia G, et al. Among authors: zentgraf h. Nat Commun. 2016 Mar 7;7:10764. doi: 10.1038/ncomms10764. Nat Commun. 2016. PMID: 26948869 Free PMC article.
The PEA-15 protein regulates autophagy via activation of JNK.
Böck BC, Tagscherer KE, Fassl A, Krämer A, Oehme I, Zentgraf HW, Keith M, Roth W. Böck BC, et al. J Biol Chem. 2010 Jul 9;285(28):21644-54. doi: 10.1074/jbc.M109.096628. Epub 2010 May 7. J Biol Chem. 2010. PMID: 20452983 Free PMC article.
238 results