Meininger D - Search Results

1

Molecular basis of sphingosine kinase 1 substrate recognition and catalysis.

Wang Z, Min X, Xiao SH, Johnstone S, Romanow W, Meininger D, Xu H, Liu J, Dai J, An S, Thibault S, Walker N. Wang Z, et al. Among authors: meininger d. Structure. 2013 May 7;21(5):798-809. doi: 10.1016/j.str.2013.02.025. Epub 2013 Apr 18. Structure. 2013. PMID: 23602659 Free article.

2

Distinctive molecular inhibition mechanisms for selective inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1.

Tu H, Powers JP, Liu J, Ursu S, Sudom A, Yan X, Xu H, Meininger D, Degraffenreid M, He X, Jaen JC, Sun D, Labelle M, Yamamoto H, Shan B, Walker NP, Wang Z. Tu H, et al. Among authors: meininger d. Bioorg Med Chem. 2008 Oct 1;16(19):8922-31. doi: 10.1016/j.bmc.2008.08.065. Epub 2008 Aug 29. Bioorg Med Chem. 2008. PMID: 18789704

3

The high-resolution crystal structure of human LCAT.

Piper DE, Romanow WG, Gunawardane RN, Fordstrom P, Masterman S, Pan O, Thibault ST, Zhang R, Meininger D, Schwarz M, Wang Z, King C, Zhou M, Walker NP. Piper DE, et al. Among authors: meininger d. J Lipid Res. 2015 Sep;56(9):1711-9. doi: 10.1194/jlr.M059873. Epub 2015 Jul 20. J Lipid Res. 2015. PMID: 26195816 Free PMC article.

4

Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers.

Herter S, Piper DE, Aaron W, Gabriele T, Cutler G, Cao P, Bhatt AS, Choe Y, Craik CS, Walker N, Meininger D, Hoey T, Austin RJ. Herter S, et al. Among authors: meininger d. Biochem J. 2005 Aug 15;390(Pt 1):125-36. doi: 10.1042/BJ20041955. Biochem J. 2005. PMID: 15839837 Free PMC article.

5

Agonistic Human Antibodies Binding to Lecithin-Cholesterol Acyltransferase Modulate High Density Lipoprotein Metabolism.

Gunawardane RN, Fordstrom P, Piper DE, Masterman S, Siu S, Liu D, Brown M, Lu M, Tang J, Zhang R, Cheng J, Gates A, Meininger D, Chan J, Carlson T, Walker N, Schwarz M, Delaney J, Zhou M. Gunawardane RN, et al. Among authors: meininger d. J Biol Chem. 2016 Feb 5;291(6):2799-811. doi: 10.1074/jbc.M115.672790. Epub 2015 Dec 7. J Biol Chem. 2016. PMID: 26644477 Free PMC article.

6

Purification and kinetic characterization of human indoleamine 2,3-dioxygenases 1 and 2 (IDO1 and IDO2) and discovery of selective IDO1 inhibitors.

Meininger D, Zalameda L, Liu Y, Stepan LP, Borges L, McCarter JD, Sutherland CL. Meininger D, et al. Biochim Biophys Acta. 2011 Dec;1814(12):1947-54. doi: 10.1016/j.bbapap.2011.07.023. Epub 2011 Jul 31. Biochim Biophys Acta. 2011. PMID: 21835273

7

Fusion partners can increase the expression of recombinant interleukins via transient transfection in 2936E cells.

Carter J, Zhang J, Dang TL, Hasegawa H, Cheng JD, Gianan I, O'Neill JW, Wolfson M, Siu S, Qu S, Meininger D, Kim H, Delaney J, Mehlin C. Carter J, et al. Among authors: meininger d. Protein Sci. 2010 Feb;19(2):357-62. doi: 10.1002/pro.307. Protein Sci. 2010. PMID: 20014434 Free PMC article.

8

In vitro modulation of cytochrome P450 reductase supported indoleamine 2,3-dioxygenase activity by allosteric effectors cytochrome b(5) and methylene blue.

Pearson JT, Siu S, Meininger DP, Wienkers LC, Rock DA. Pearson JT, et al. Biochemistry. 2010 Mar 30;49(12):2647-56. doi: 10.1021/bi100022c. Biochemistry. 2010. PMID: 20178337

9

AMG 595, an Anti-EGFRvIII Antibody-Drug Conjugate, Induces Potent Antitumor Activity against EGFRvIII-Expressing Glioblastoma.

Hamblett KJ, Kozlosky CJ, Siu S, Chang WS, Liu H, Foltz IN, Trueblood ES, Meininger D, Arora T, Twomey B, Vonderfecht SL, Chen Q, Hill JS, Fanslow WC. Hamblett KJ, et al. Among authors: meininger d. Mol Cancer Ther. 2015 Jul;14(7):1614-24. doi: 10.1158/1535-7163.MCT-14-1078. Epub 2015 Apr 30. Mol Cancer Ther. 2015. PMID: 25931519

10

Systems-based design of bi-ligand inhibitors of oxidoreductases: filling the chemical proteomic toolbox.

Sem DS, Bertolaet B, Baker B, Chang E, Costache AD, Coutts S, Dong Q, Hansen M, Hong V, Huang X, Jack RM, Kho R, Lang H, Ma CT, Meininger D, Pellecchia M, Pierre F, Villar H, Yu L. Sem DS, et al. Among authors: meininger d. Chem Biol. 2004 Feb;11(2):185-94. doi: 10.1016/j.chembiol.2004.02.012. Chem Biol. 2004. PMID: 15123280

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