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Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitors.
Morris EJ, Jha S, Restaino CR, Dayananth P, Zhu H, Cooper A, Carr D, Deng Y, Jin W, Black S, Long B, Liu J, Dinunzio E, Windsor W, Zhang R, Zhao S, Angagaw MH, Pinheiro EM, Desai J, Xiao L, Shipps G, Hruza A, Wang J, Kelly J, Paliwal S, Gao X, Babu BS, Zhu L, Daublain P, Zhang L, Lutterbach BA, Pelletier MR, Philippar U, Siliphaivanh P, Witter D, Kirschmeier P, Bishop WR, Hicklin D, Gilliland DG, Jayaraman L, Zawel L, Fawell S, Samatar AA. Morris EJ, et al. Among authors: jha s. Cancer Discov. 2013 Jul;3(7):742-50. doi: 10.1158/2159-8290.CD-13-0070. Epub 2013 Apr 24. Cancer Discov. 2013. PMID: 23614898
Dissecting Therapeutic Resistance to ERK Inhibition.
Jha S, Morris EJ, Hruza A, Mansueto MS, Schroeder GK, Arbanas J, McMasters D, Restaino CR, Dayananth P, Black S, Elsen NL, Mannarino A, Cooper A, Fawell S, Zawel L, Jayaraman L, Samatar AA. Jha S, et al. Mol Cancer Ther. 2016 Apr;15(4):548-59. doi: 10.1158/1535-7163.MCT-15-0172. Epub 2016 Feb 1. Mol Cancer Ther. 2016. PMID: 26832798
Combination of the mTOR inhibitor ridaforolimus and the anti-IGF1R monoclonal antibody dalotuzumab: preclinical characterization and phase I clinical trial.
Di Cosimo S, Sathyanarayanan S, Bendell JC, Cervantes A, Stein MN, Braña I, Roda D, Haines BB, Zhang T, Winter CG, Jha S, Xu Y, Frazier J, Klinghoffer RA, Leighton-Swayze A, Song Y, Ebbinghaus S, Baselga J. Di Cosimo S, et al. Among authors: jha s. Clin Cancer Res. 2015 Jan 1;21(1):49-59. doi: 10.1158/1078-0432.CCR-14-0940. Epub 2014 Oct 15. Clin Cancer Res. 2015. PMID: 25320355 Free PMC article. Clinical Trial.
A first-in-human study of the anti-LAG-3 antibody favezelimab plus pembrolizumab in previously treated, advanced microsatellite stable colorectal cancer.
Garralda E, Sukari A, Lakhani NJ, Patnaik A, Lou Y, Im SA, Golan T, Geva R, Wermke M, de Miguel M, Palcza J, Jha S, Chaney M, Abraham AK, Healy J, Falchook GS. Garralda E, et al. Among authors: jha s. ESMO Open. 2022 Dec;7(6):100639. doi: 10.1016/j.esmoop.2022.100639. Epub 2022 Dec 6. ESMO Open. 2022. PMID: 36493599 Free PMC article.
Rapid climate action is needed: comparing heat vs. COVID-19-related mortality.
Batibeniz F, Seneviratne SI, Jha S, Ribeiro A, Suarez Gutierrez L, Raible CC, Malhotra A, Armstrong B, Bell ML, Lavigne E, Gasparrini A, Guo Y, Hashizume M, Masselot P, da Silva SP, Royé D, Sera F, Tong S, Urban A, Vicedo-Cabrera AM. Batibeniz F, et al. Among authors: jha s. Sci Rep. 2025 Jan 6;15(1):1002. doi: 10.1038/s41598-024-82788-8. Sci Rep. 2025. PMID: 39762298 Free PMC article.
Land Use Change Consistently Reduces α- But Not β- and γ-Diversity of Bees.
Tsang TPN, De Santis AAA, Armas-Quiñonez G, Ascher JS, Ávila-Gómez ES, Báldi A, Ballare KM, Balzan MV, Banaszak-Cibicka W, Bänsch S, Basset Y, Bates AJ, Baumann JM, Beal-Neves M, Bennett A, Bezerra ADM, Blochtein B, Bommarco R, Brosi B, Burkle LA, Carvalheiro LG, Castellanos I, Cely-Santos M, Cohen H, Coulibaly D, Cunningham SA, Cusser S, Dajoz I, Delaney DA, Del-Val E, Egerer M, Eichhorn MP, Enríquez E, Entling MH, Escobedo-Kenefic N, Ferreira PMA, Fitch G, Forrest JRK, Fournier V, Fowler R, Freitas BM, Gaines-Day HR, Geslin B, Ghazoul J, Glaum P, Gonzalez-Andujar JL, González-Chaves A, Grab H, Gratton C, Guenat S, Gutiérrez-Chacón C, Hall MA, Hanley ME, Hass A, Hennig EI, Hermy M, Hipólito J, Holzschuh A, Hopfenmüller S, Hung KJ, Hylander K, Izquierdo J, Jamieson MA, Jauker B, Javorek S, Jha S, Klatt BK, Kleijn D, Klein AM, Kovács-Hostyánszki A, Krauss J, Kuhlmann M, Landaverde-González P, Latty T, Leong M, Lerman SB, Liu Y, Machado ACP, Main A, Mallinger R, Mandelik Y, Marques BF, Matteson K, McCune F, Meng LZ, Metzger JP, Montoya-Pfeiffer PM, Morales C, Morandin L, Morrison J, Mudri-Stojnić S, Nalinrachatakan P, Norfolk O, Otieno M, Park MG, Philpott SM, Pisanty G, Plas… See abstract for full author list ➔ Tsang TPN, et al. Among authors: jha s. Glob Chang Biol. 2025 Jan;31(1):e70006. doi: 10.1111/gcb.70006. Glob Chang Biol. 2025. PMID: 39754379
2,149 results