Mills GB - Search Results

1

Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkers.

Lui VW, Hedberg ML, Li H, Vangara BS, Pendleton K, Zeng Y, Lu Y, Zhang Q, Du Y, Gilbert BR, Freilino M, Sauerwein S, Peyser ND, Xiao D, Diergaarde B, Wang L, Chiosea S, Seethala R, Johnson JT, Kim S, Duvvuri U, Ferris RL, Romkes M, Nukui T, Kwok-Shing Ng P, Garraway LA, Hammerman PS, Mills GB, Grandis JR. Lui VW, et al. Among authors: mills gb. Cancer Discov. 2013 Jul;3(7):761-9. doi: 10.1158/2159-8290.CD-13-0103. Epub 2013 Apr 25. Cancer Discov. 2013. PMID: 23619167 Free PMC article.

2

Linking molecular therapeutics to molecular diagnostics: inhibition of the FRAP/RAFT/TOR component of the PI3K pathway preferentially blocks PTEN mutant cells in vitro and in vivo.

Mills GB, Lu Y, Kohn EC. Mills GB, et al. Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10031-3. doi: 10.1073/pnas.191379498. Proc Natl Acad Sci U S A. 2001. PMID: 11526226 Free PMC article. No abstract available.

3

Inhibition of phosphatidylinositol 3'-kinase increases efficacy of paclitaxel in in vitro and in vivo ovarian cancer models.

Hu L, Hofmann J, Lu Y, Mills GB, Jaffe RB. Hu L, et al. Among authors: mills gb. Cancer Res. 2002 Feb 15;62(4):1087-92. Cancer Res. 2002. PMID: 11861387

4

Insulin-like growth factor-I inhibits progesterone receptor expression in breast cancer cells via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway: progesterone receptor as a potential indicator of growth factor activity in breast cancer.

Cui X, Zhang P, Deng W, Oesterreich S, Lu Y, Mills GB, Lee AV. Cui X, et al. Among authors: mills gb. Mol Endocrinol. 2003 Apr;17(4):575-88. doi: 10.1210/me.2002-0318. Epub 2003 Jan 2. Mol Endocrinol. 2003. PMID: 12554765

5

Targeting PI3K-AKT pathway for cancer therapy.

Lu Y, Wang H, Mills GB. Lu Y, et al. Among authors: mills gb. Rev Clin Exp Hematol. 2003 Jun;7(2):205-28. Rev Clin Exp Hematol. 2003. PMID: 14763163 Review.

6

The Akt inhibitor KP372-1 suppresses Akt activity and cell proliferation and induces apoptosis in thyroid cancer cells.

Mandal M, Kim S, Younes MN, Jasser SA, El-Naggar AK, Mills GB, Myers JN. Mandal M, et al. Among authors: mills gb. Br J Cancer. 2005 May 23;92(10):1899-905. doi: 10.1038/sj.bjc.6602595. Br J Cancer. 2005. Retraction in: Br J Cancer. 2021 May;124(10):1747. doi: 10.1038/s41416-021-01299-9. PMID: 15870708 Free PMC article. Retracted.

7

Exploiting the PI3K/AKT pathway for cancer drug discovery.

Hennessy BT, Smith DL, Ram PT, Lu Y, Mills GB. Hennessy BT, et al. Among authors: mills gb. Nat Rev Drug Discov. 2005 Dec;4(12):988-1004. doi: 10.1038/nrd1902. Nat Rev Drug Discov. 2005. PMID: 16341064 Review.

8

Assay of Rab25 function in ovarian and breast cancers.

Cheng KW, Lu Y, Mills GB. Cheng KW, et al. Among authors: mills gb. Methods Enzymol. 2005;403:202-15. doi: 10.1016/S0076-6879(05)03017-X. Methods Enzymol. 2005. PMID: 16473588

9

Phosphorylation of TNF-alpha converting enzyme by gastrin-releasing peptide induces amphiregulin release and EGF receptor activation.

Zhang Q, Thomas SM, Lui VW, Xi S, Siegfried JM, Fan H, Smithgall TE, Mills GB, Grandis JR. Zhang Q, et al. Among authors: mills gb. Proc Natl Acad Sci U S A. 2006 May 2;103(18):6901-6. doi: 10.1073/pnas.0509719103. Epub 2006 Apr 25. Proc Natl Acad Sci U S A. 2006. PMID: 16641105 Free PMC article.

10

Antitumor mechanisms of combined gastrin-releasing peptide receptor and epidermal growth factor receptor targeting in head and neck cancer.

Zhang Q, Bhola NE, Lui VW, Siwak DR, Thomas SM, Gubish CT, Siegfried JM, Mills GB, Shin D, Grandis JR. Zhang Q, et al. Among authors: mills gb. Mol Cancer Ther. 2007 Apr;6(4):1414-24. doi: 10.1158/1535-7163.MCT-06-0678. Mol Cancer Ther. 2007. PMID: 17431120 Free article.

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