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Synthesis, activity, and structural analysis of novel α-hydroxytropolone inhibitors of human immunodeficiency virus reverse transcriptase-associated ribonuclease H.
Chung S, Himmel DM, Jiang JK, Wojtak K, Bauman JD, Rausch JW, Wilson JA, Beutler JA, Thomas CJ, Arnold E, Le Grice SF. Chung S, et al. Among authors: le grice sf. J Med Chem. 2011 Jul 14;54(13):4462-73. doi: 10.1021/jm2000757. Epub 2011 Jun 2. J Med Chem. 2011. PMID: 21568335 Free PMC article.
Scaffold hopping and optimisation of 3',4'-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H.
Tocco G, Esposito F, Caboni P, Laus A, Beutler JA, Wilson JA, Corona A, Le Grice SFJ, Tramontano E. Tocco G, et al. Among authors: le grice sfj. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1953-1963. doi: 10.1080/14756366.2020.1835884. J Enzyme Inhib Med Chem. 2020. PMID: 33143469 Free PMC article.
246 results