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The TLR4 antagonist Eritoran protects mice from lethal influenza infection.
Shirey KA, Lai W, Scott AJ, Lipsky M, Mistry P, Pletneva LM, Karp CL, McAlees J, Gioannini TL, Weiss J, Chen WH, Ernst RK, Rossignol DP, Gusovsky F, Blanco JC, Vogel SN. Shirey KA, et al. Among authors: scott aj. Nature. 2013 May 23;497(7450):498-502. doi: 10.1038/nature12118. Epub 2013 May 1. Nature. 2013. PMID: 23636320 Free PMC article.
Type IV pili promote early biofilm formation by Clostridium difficile.
Maldarelli GA, Piepenbrink KH, Scott AJ, Freiberg JA, Song Y, Achermann Y, Ernst RK, Shirtliff ME, Sundberg EJ, Donnenberg MS, von Rosenvinge EC. Maldarelli GA, et al. Among authors: scott aj. Pathog Dis. 2016 Aug;74(6):ftw061. doi: 10.1093/femspd/ftw061. Epub 2016 Jun 30. Pathog Dis. 2016. PMID: 27369898 Free PMC article.
Infection-derived lipids elicit an immune deficiency circuit in arthropods.
Shaw DK, Wang X, Brown LJ, Chávez AS, Reif KE, Smith AA, Scott AJ, McClure EE, Boradia VM, Hammond HL, Sundberg EJ, Snyder GA, Liu L, DePonte K, Villar M, Ueti MW, de la Fuente J, Ernst RK, Pal U, Fikrig E, Pedra JH. Shaw DK, et al. Among authors: scott aj. Nat Commun. 2017 Feb 14;8:14401. doi: 10.1038/ncomms14401. Nat Commun. 2017. PMID: 28195158 Free PMC article.
Host-based lipid inflammation drives pathogenesis in Francisella infection.
Scott AJ, Post JM, Lerner R, Ellis SR, Lieberman J, Shirey KA, Heeren RMA, Bindila L, Ernst RK. Scott AJ, et al. Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):12596-12601. doi: 10.1073/pnas.1712887114. Epub 2017 Nov 6. Proc Natl Acad Sci U S A. 2017. PMID: 29109289 Free PMC article.
388 results