Okigaki M - Search Results

1

Distinct role of Pyk2 in mediating thromboxane generation downstream of both G12/13 and integrin αIIbβ3 in platelets.

Kim S, Cipolla L, Guidetti G, Okigaki M, Jin J, Torti M, Kunapuli SP. Kim S, et al. Among authors: okigaki m. J Biol Chem. 2013 Jun 21;288(25):18194-203. doi: 10.1074/jbc.M113.461087. Epub 2013 May 2. J Biol Chem. 2013. PMID: 23640884 Free PMC article.

2

Activation of phosphatidylinositol 3-kinase β by the platelet collagen receptors integrin α2β1 and GPVI: The role of Pyk2 and c-Cbl.

Manganaro D, Consonni A, Guidetti GF, Canobbio I, Visconte C, Kim S, Okigaki M, Falasca M, Hirsch E, Kunapuli SP, Torti M. Manganaro D, et al. Among authors: okigaki m. Biochim Biophys Acta. 2015 Aug;1853(8):1879-88. doi: 10.1016/j.bbamcr.2015.05.004. Epub 2015 May 8. Biochim Biophys Acta. 2015. PMID: 25960397 Free article.

3

The focal adhesion kinase Pyk2 links Ca2+ signalling to Src family kinase activation and protein tyrosine phosphorylation in thrombin-stimulated platelets.

Canobbio I, Cipolla L, Guidetti GF, Manganaro D, Visconte C, Kim S, Okigaki M, Falasca M, Kunapuli SP, Torti M. Canobbio I, et al. Among authors: okigaki m. Biochem J. 2015 Jul 15;469(2):199-210. doi: 10.1042/BJ20150048. Epub 2015 May 13. Biochem J. 2015. PMID: 25967238

4

Role and regulation of phosphatidylinositol 3-kinase β in platelet integrin α2β1 signaling.

Consonni A, Cipolla L, Guidetti G, Canobbio I, Ciraolo E, Hirsch E, Falasca M, Okigaki M, Balduini C, Torti M. Consonni A, et al. Among authors: okigaki m. Blood. 2012 Jan 19;119(3):847-56. doi: 10.1182/blood-2011-07-364992. Epub 2011 Nov 21. Blood. 2012. PMID: 22106345 Free article.

5

Impaired thrombin-induced platelet activation and thrombus formation in mice lacking the Ca(2+)-dependent tyrosine kinase Pyk2.

Canobbio I, Cipolla L, Consonni A, Momi S, Guidetti G, Oliviero B, Falasca M, Okigaki M, Balduini C, Gresele P, Torti M. Canobbio I, et al. Among authors: okigaki m. Blood. 2013 Jan 24;121(4):648-57. doi: 10.1182/blood-2012-06-438762. Epub 2012 Nov 21. Blood. 2013. PMID: 23175689 Free article.

6

The proline-rich tyrosine kinase Pyk2 regulates platelet integrin αIIbβ3 outside-in signaling.

Cipolla L, Consonni A, Guidetti G, Canobbio I, Okigaki M, Falasca M, Ciraolo E, Hirsch E, Balduini C, Torti M. Cipolla L, et al. Among authors: okigaki m. J Thromb Haemost. 2013 Feb;11(2):345-56. doi: 10.1111/jth.12099. J Thromb Haemost. 2013. PMID: 23216754 Free article.

7

Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade.

Andreev J, Galisteo ML, Kranenburg O, Logan SK, Chiu ES, Okigaki M, Cary LA, Moolenaar WH, Schlessinger J. Andreev J, et al. Among authors: okigaki m. J Biol Chem. 2001 Jun 8;276(23):20130-5. doi: 10.1074/jbc.M102307200. Epub 2001 Mar 27. J Biol Chem. 2001. PMID: 11274221 Free article.

8

Pyk2 regulates multiple signaling events crucial for macrophage morphology and migration.

Okigaki M, Davis C, Falasca M, Harroch S, Felsenfeld DP, Sheetz MP, Schlessinger J. Okigaki M, et al. Proc Natl Acad Sci U S A. 2003 Sep 16;100(19):10740-5. doi: 10.1073/pnas.1834348100. Epub 2003 Sep 5. Proc Natl Acad Sci U S A. 2003. PMID: 12960403 Free PMC article.

9

Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response.

Guinamard R, Okigaki M, Schlessinger J, Ravetch JV. Guinamard R, et al. Among authors: okigaki m. Nat Immunol. 2000 Jul;1(1):31-6. doi: 10.1038/76882. Nat Immunol. 2000. PMID: 10881171

10

No obvious abnormality in mice deficient in receptor protein tyrosine phosphatase beta.

Harroch S, Palmeri M, Rosenbluth J, Custer A, Okigaki M, Shrager P, Blum M, Buxbaum JD, Schlessinger J. Harroch S, et al. Among authors: okigaki m. Mol Cell Biol. 2000 Oct;20(20):7706-15. doi: 10.1128/MCB.20.20.7706-7715.2000. Mol Cell Biol. 2000. PMID: 11003666 Free PMC article.

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