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834 results

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Page 1
A role for cytosolic fumarate hydratase in urea cycle metabolism and renal neoplasia.
Adam J, Yang M, Bauerschmidt C, Kitagawa M, O'Flaherty L, Maheswaran P, Özkan G, Sahgal N, Baban D, Kato K, Saito K, Iino K, Igarashi K, Stratford M, Pugh C, Tennant DA, Ludwig C, Davies B, Ratcliffe PJ, El-Bahrawy M, Ashrafian H, Soga T, Pollard PJ. Adam J, et al. Among authors: ludwig c. Cell Rep. 2013 May 30;3(5):1440-8. doi: 10.1016/j.celrep.2013.04.006. Epub 2013 May 2. Cell Rep. 2013. PMID: 23643539 Free PMC article.
Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway.
Ashrafian H, Czibik G, Bellahcene M, Aksentijević D, Smith AC, Mitchell SJ, Dodd MS, Kirwan J, Byrne JJ, Ludwig C, Isackson H, Yavari A, Støttrup NB, Contractor H, Cahill TJ, Sahgal N, Ball DR, Birkler RI, Hargreaves I, Tennant DA, Land J, Lygate CA, Johannsen M, Kharbanda RK, Neubauer S, Redwood C, de Cabo R, Ahmet I, Talan M, Günther UL, Robinson AJ, Viant MR, Pollard PJ, Tyler DJ, Watkins H. Ashrafian H, et al. Among authors: ludwig c. Cell Metab. 2012 Mar 7;15(3):361-71. doi: 10.1016/j.cmet.2012.01.017. Cell Metab. 2012. PMID: 22405071 Free PMC article.
Probing Cancer Cell Metabolism Using NMR Spectroscopy.
Hollinshead KE, Williams DS, Tennant DA, Ludwig C. Hollinshead KE, et al. Among authors: ludwig c. Adv Exp Med Biol. 2016;899:89-111. doi: 10.1007/978-3-319-26666-4_6. Adv Exp Med Biol. 2016. PMID: 27325263 Review.
Combined Analysis of NMR and MS Spectra (CANMS).
Chong M, Jayaraman A, Marin S, Selivanov V, de Atauri Carulla PR, Tennant DA, Cascante M, Günther UL, Ludwig C. Chong M, et al. Among authors: ludwig c. Angew Chem Int Ed Engl. 2017 Apr 3;56(15):4140-4144. doi: 10.1002/anie.201611634. Epub 2017 Mar 8. Angew Chem Int Ed Engl. 2017. PMID: 28272839
High-Speed Tracer Analysis of Metabolism (HS-TrAM).
Smith TB, Patel K, Munford H, Peet A, Tennant DA, Jeeves M, Ludwig C. Smith TB, et al. Among authors: ludwig c. Wellcome Open Res. 2018 Jan 12;3:5. doi: 10.12688/wellcomeopenres.13387.2. eCollection 2018. Wellcome Open Res. 2018. PMID: 29503875 Free PMC article.
Oncogenic IDH1 Mutations Promote Enhanced Proline Synthesis through PYCR1 to Support the Maintenance of Mitochondrial Redox Homeostasis.
Hollinshead KER, Munford H, Eales KL, Bardella C, Li C, Escribano-Gonzalez C, Thakker A, Nonnenmacher Y, Kluckova K, Jeeves M, Murren R, Cuozzo F, Ye D, Laurenti G, Zhu W, Hiller K, Hodson DJ, Hua W, Tomlinson IP, Ludwig C, Mao Y, Tennant DA. Hollinshead KER, et al. Among authors: ludwig c. Cell Rep. 2018 Mar 20;22(12):3107-3114. doi: 10.1016/j.celrep.2018.02.084. Cell Rep. 2018. PMID: 29562167 Free PMC article.
834 results