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Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.
Bauernfeind FG, Horvath G, Stutz A, Alnemri ES, MacDonald K, Speert D, Fernandes-Alnemri T, Wu J, Monks BG, Fitzgerald KA, Hornung V, Latz E. Bauernfeind FG, et al. Among authors: fitzgerald ka. J Immunol. 2009 Jul 15;183(2):787-91. doi: 10.4049/jimmunol.0901363. Epub 2009 Jul 1. J Immunol. 2009. PMID: 19570822 Free PMC article.
Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome.
Kim S, Bauernfeind F, Ablasser A, Hartmann G, Fitzgerald KA, Latz E, Hornung V. Kim S, et al. Among authors: fitzgerald ka. Eur J Immunol. 2010 Jun;40(6):1545-51. doi: 10.1002/eji.201040425. Eur J Immunol. 2010. PMID: 20333626 Free PMC article.
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, Bauernfeind FG, Abela GS, Franchi L, Nuñez G, Schnurr M, Espevik T, Lien E, Fitzgerald KA, Rock KL, Moore KJ, Wright SD, Hornung V, Latz E. Duewell P, et al. Among authors: fitzgerald ka. Nature. 2010 Apr 29;464(7293):1357-61. doi: 10.1038/nature08938. Nature. 2010. PMID: 20428172 Free PMC article.
Catenin' on to nucleic acid sensing.
Rathinam VA, Sharma S, Fitzgerald KA. Rathinam VA, et al. Among authors: fitzgerald ka. Nat Immunol. 2010 Jun;11(6):466-8. doi: 10.1038/ni0610-466. Nat Immunol. 2010. PMID: 20485273 No abstract available.
365 results