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MMSET is the key molecular target in t(4;14) myeloma.
Mirabella F, Wu P, Wardell CP, Kaiser MF, Walker BA, Johnson DC, Morgan GJ. Mirabella F, et al. Among authors: wardell cp. Blood Cancer J. 2013 May 3;3(5):e114. doi: 10.1038/bcj.2013.9. Blood Cancer J. 2013. PMID: 23645128 Free PMC article. No abstract available.
Improved risk stratification in myeloma using a microRNA-based classifier.
Wu P, Agnelli L, Walker BA, Todoerti K, Lionetti M, Johnson DC, Kaiser M, Mirabella F, Wardell C, Gregory WM, Davies FE, Brewer D, Neri A, Morgan GJ. Wu P, et al. Br J Haematol. 2013 Aug;162(3):348-59. doi: 10.1111/bjh.12394. Epub 2013 May 30. Br J Haematol. 2013. PMID: 23718138 Free article.
Neutral tumor evolution in myeloma is associated with poor prognosis.
Johnson DC, Lenive O, Mitchell J, Jackson G, Owen R, Drayson M, Cook G, Jones JR, Pawlyn C, Davies FE, Walker BA, Wardell C, Gregory WM, Cairns D, Morgan GJ, Houlston RS, Kaiser MF. Johnson DC, et al. Blood. 2017 Oct 5;130(14):1639-1643. doi: 10.1182/blood-2016-11-750612. Epub 2017 Aug 21. Blood. 2017. PMID: 28827410 Free PMC article. Clinical Trial.
Single-cell genetic analysis reveals the composition of initiating clones and phylogenetic patterns of branching and parallel evolution in myeloma.
Melchor L, Brioli A, Wardell CP, Murison A, Potter NE, Kaiser MF, Fryer RA, Johnson DC, Begum DB, Hulkki Wilson S, Vijayaraghavan G, Titley I, Cavo M, Davies FE, Walker BA, Morgan GJ. Melchor L, et al. Among authors: wardell cp. Leukemia. 2014 Aug;28(8):1705-15. doi: 10.1038/leu.2014.13. Epub 2014 Jan 13. Leukemia. 2014. PMID: 24480973
66 results