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Phosphorylation of KRAB-associated protein 1 (KAP1) at Tyr-449, Tyr-458, and Tyr-517 by nuclear tyrosine kinases inhibits the association of KAP1 and heterochromatin protein 1α (HP1α) with heterochromatin.
Kubota S, Fukumoto Y, Aoyama K, Ishibashi K, Yuki R, Morinaga T, Honda T, Yamaguchi N, Kuga T, Tomonaga T, Yamaguchi N. Kubota S, et al. Among authors: aoyama k. J Biol Chem. 2013 Jun 14;288(24):17871-83. doi: 10.1074/jbc.M112.437756. Epub 2013 May 4. J Biol Chem. 2013. PMID: 23645696 Free PMC article.
Activation of the prereplication complex is blocked by mimosine through reactive oxygen species-activated ataxia telangiectasia mutated (ATM) protein without DNA damage.
Kubota S, Fukumoto Y, Ishibashi K, Soeda S, Kubota S, Yuki R, Nakayama Y, Aoyama K, Yamaguchi N, Yamaguchi N. Kubota S, et al. Among authors: aoyama k. J Biol Chem. 2014 Feb 28;289(9):5730-46. doi: 10.1074/jbc.M113.546655. Epub 2014 Jan 13. J Biol Chem. 2014. PMID: 24421316 Free PMC article.
765 results