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Prolonged lifespan with enhanced exploratory behavior in mice overexpressing the oxidized nucleoside triphosphatase hMTH1.
De Luca G, Ventura I, Sanghez V, Russo MT, Ajmone-Cat MA, Cacci E, Martire A, Popoli P, Falcone G, Michelini F, Crescenzi M, Degan P, Minghetti L, Bignami M, Calamandrei G. De Luca G, et al. Among authors: bignami m. Aging Cell. 2013 Aug;12(4):695-705. doi: 10.1111/acel.12094. Epub 2013 May 30. Aging Cell. 2013. PMID: 23648059 Free article.
A role for oxidized DNA precursors in Huntington's disease-like striatal neurodegeneration.
De Luca G, Russo MT, Degan P, Tiveron C, Zijno A, Meccia E, Ventura I, Mattei E, Nakabeppu Y, Crescenzi M, Pepponi R, Pèzzola A, Popoli P, Bignami M. De Luca G, et al. Among authors: bignami m. PLoS Genet. 2008 Nov;4(11):e1000266. doi: 10.1371/journal.pgen.1000266. Epub 2008 Nov 21. PLoS Genet. 2008. PMID: 19023407 Free PMC article.
Understanding the role of the Q338H MUTYH variant in oxidative damage repair.
Turco E, Ventura I, Minoprio A, Russo MT, Torreri P, Degan P, Molatore S, Ranzani GN, Bignami M, Mazzei F. Turco E, et al. Among authors: bignami m. Nucleic Acids Res. 2013 Apr;41(7):4093-103. doi: 10.1093/nar/gkt130. Epub 2013 Mar 4. Nucleic Acids Res. 2013. PMID: 23460202 Free PMC article.
Young transgenic hMTH1 mice are protected against dietary fat-induced metabolic stress-implications for enhanced longevity.
Marcon F, Meschini R, Iorio E, Palleschi S, De Luca G, Siniscalchi E, Conti L, Chirico M, Pisanu ME, De Battistis F, Rossi B, Minoprio A, Giuliani A, Karran P, Bignami M. Marcon F, et al. Among authors: bignami m. Aging Cell. 2022 Jul;21(7):e13605. doi: 10.1111/acel.13605. Epub 2022 Jun 6. Aging Cell. 2022. PMID: 35670027 Free PMC article.
318 results