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New regulators of Wnt/beta-catenin signaling revealed by integrative molecular screening.
Major MB, Roberts BS, Berndt JD, Marine S, Anastas J, Chung N, Ferrer M, Yi X, Stoick-Cooper CL, von Haller PD, Kategaya L, Chien A, Angers S, MacCoss M, Cleary MA, Arthur WT, Moon RT. Major MB, et al. Among authors: berndt jd. Sci Signal. 2008 Nov 11;1(45):ra12. doi: 10.1126/scisignal.2000037. Sci Signal. 2008. PMID: 19001663
Altered splicing of ATP6AP2 causes X-linked parkinsonism with spasticity (XPDS).
Korvatska O, Strand NS, Berndt JD, Strovas T, Chen DH, Leverenz JB, Kiianitsa K, Mata IF, Karakoc E, Greenup JL, Bonkowski E, Chuang J, Moon RT, Eichler EE, Nickerson DA, Zabetian CP, Kraemer BC, Bird TD, Raskind WH. Korvatska O, et al. Among authors: berndt jd. Hum Mol Genet. 2013 Aug 15;22(16):3259-68. doi: 10.1093/hmg/ddt180. Epub 2013 Apr 16. Hum Mol Genet. 2013. PMID: 23595882 Free PMC article.
USP6 oncogene promotes Wnt signaling by deubiquitylating Frizzleds.
Madan B, Walker MP, Young R, Quick L, Orgel KA, Ryan M, Gupta P, Henrich IC, Ferrer M, Marine S, Roberts BS, Arthur WT, Berndt JD, Oliveira AM, Moon RT, Virshup DM, Chou MM, Major MB. Madan B, et al. Proc Natl Acad Sci U S A. 2016 May 24;113(21):E2945-54. doi: 10.1073/pnas.1605691113. Epub 2016 May 9. Proc Natl Acad Sci U S A. 2016. PMID: 27162353 Free PMC article.
Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling.
Major MB, Camp ND, Berndt JD, Yi X, Goldenberg SJ, Hubbert C, Biechele TL, Gingras AC, Zheng N, Maccoss MJ, Angers S, Moon RT. Major MB, et al. Among authors: berndt jd. Science. 2007 May 18;316(5827):1043-6. doi: 10.1126/science/1141515. Science. 2007. PMID: 17510365
Cell biology. Making a point with Wnt signals.
Berndt JD, Moon RT. Berndt JD, et al. Science. 2013 Mar 22;339(6126):1388-9. doi: 10.1126/science.1236641. Science. 2013. PMID: 23520097 No abstract available.
213 results