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Optimization of triazine nitriles as rhodesain inhibitors: structure-activity relationships, bioisosteric imidazopyridine nitriles, and X-ray crystal structure analysis with human cathepsin L.
Ehmke V, Winkler E, Banner DW, Haap W, Schweizer WB, Rottmann M, Kaiser M, Freymond C, Schirmeister T, Diederich F. Ehmke V, et al. Among authors: schirmeister t. ChemMedChem. 2013 Jun;8(6):967-75. doi: 10.1002/cmdc.201300112. Epub 2013 May 9. ChemMedChem. 2013. PMID: 23658062
Development of rhodesain inhibitors with a 3-bromoisoxazoline warhead.
Ettari R, Tamborini L, Angelo IC, Grasso S, Schirmeister T, Lo Presti L, De Micheli C, Pinto A, Conti P. Ettari R, et al. Among authors: schirmeister t. ChemMedChem. 2013 Dec;8(12):2070-6. doi: 10.1002/cmdc.201300390. Epub 2013 Nov 15. ChemMedChem. 2013. PMID: 24243827
Synthesis and biological evaluation of papain-family cathepsin L-like cysteine protease inhibitors containing a 1,4-benzodiazepine scaffold as antiprotozoal agents.
Ettari R, Pinto A, Tamborini L, Angelo IC, Grasso S, Zappalà M, Capodicasa N, Yzeiraj L, Gruber E, Aminake MN, Pradel G, Schirmeister T, De Micheli C, Conti P. Ettari R, et al. Among authors: schirmeister t. ChemMedChem. 2014 Aug;9(8):1817-25. doi: 10.1002/cmdc.201402079. Epub 2014 Jun 11. ChemMedChem. 2014. PMID: 24919925
208 results