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STAT5A/B gene locus undergoes amplification during human prostate cancer progression.
Haddad BR, Gu L, Mirtti T, Dagvadorj A, Vogiatzi P, Hoang DT, Bajaj R, Leiby B, Ellsworth E, Blackmon S, Ruiz C, Curtis M, Fortina P, Ertel A, Liu C, Rui H, Visakorpi T, Bubendorf L, Lallas CD, Trabulsi EJ, McCue P, Gomella L, Nevalainen MT. Haddad BR, et al. Among authors: liu c. Am J Pathol. 2013 Jun;182(6):2264-75. doi: 10.1016/j.ajpath.2013.02.044. Epub 2013 May 7. Am J Pathol. 2013. PMID: 23660011 Free PMC article.
PTP1B suppresses prolactin activation of Stat5 in breast cancer cells.
Johnson KJ, Peck AR, Liu C, Tran TH, Utama FE, Sjolund AB, Schaber JD, Witkiewicz AK, Rui H. Johnson KJ, et al. Among authors: liu c. Am J Pathol. 2010 Dec;177(6):2971-83. doi: 10.2353/ajpath.2010.090399. Epub 2010 Oct 15. Am J Pathol. 2010. PMID: 20952588 Free PMC article.
Loss of nuclear localized and tyrosine phosphorylated Stat5 in breast cancer predicts poor clinical outcome and increased risk of antiestrogen therapy failure.
Peck AR, Witkiewicz AK, Liu C, Stringer GA, Klimowicz AC, Pequignot E, Freydin B, Tran TH, Yang N, Rosenberg AL, Hooke JA, Kovatich AJ, Nevalainen MT, Shriver CD, Hyslop T, Sauter G, Rimm DL, Magliocco AM, Rui H. Peck AR, et al. Among authors: liu c. J Clin Oncol. 2011 Jun 20;29(18):2448-58. doi: 10.1200/JCO.2010.30.3552. Epub 2011 May 16. J Clin Oncol. 2011. PMID: 21576635 Free PMC article.
Low levels of Stat5a protein in breast cancer are associated with tumor progression and unfavorable clinical outcomes.
Peck AR, Witkiewicz AK, Liu C, Klimowicz AC, Stringer GA, Pequignot E, Freydin B, Yang N, Ertel A, Tran TH, Girondo MA, Rosenberg AL, Hooke JA, Kovatich AJ, Shriver CD, Rimm DL, Magliocco AM, Hyslop T, Rui H. Peck AR, et al. Among authors: liu c. Breast Cancer Res. 2012 Oct 4;14(5):R130. doi: 10.1186/bcr3328. Breast Cancer Res. 2012. PMID: 23036105 Free PMC article.
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