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An FGF21-adiponectin-ceramide axis controls energy expenditure and insulin action in mice.
Holland WL, Adams AC, Brozinick JT, Bui HH, Miyauchi Y, Kusminski CM, Bauer SM, Wade M, Singhal E, Cheng CC, Volk K, Kuo MS, Gordillo R, Kharitonenkov A, Scherer PE. Holland WL, et al. Among authors: adams ac. Cell Metab. 2013 May 7;17(5):790-7. doi: 10.1016/j.cmet.2013.03.019. Cell Metab. 2013. PMID: 23663742 Free PMC article.
Inventing new medicines: The FGF21 story.
Kharitonenkov A, Adams AC. Kharitonenkov A, et al. Among authors: adams ac. Mol Metab. 2013 Dec 27;3(3):221-9. doi: 10.1016/j.molmet.2013.12.003. eCollection 2014 Jun. Mol Metab. 2013. PMID: 24749049 Free PMC article. Review.
FGF21 Is an Insulin-Dependent Postprandial Hormone in Adult Humans.
Samms RJ, Lewis JE, Norton L, Stephens FB, Gaffney CJ, Butterfield T, Smith DP, Cheng CC, Perfield JW 2nd, Adams AC, Ebling FJP, Tsintzas K. Samms RJ, et al. Among authors: adams ac. J Clin Endocrinol Metab. 2017 Oct 1;102(10):3806-3813. doi: 10.1210/jc.2017-01257. J Clin Endocrinol Metab. 2017. PMID: 28938434 Free PMC article. Clinical Trial.
The anti-obesity effect of FGF19 does not require UCP1-dependent thermogenesis.
Antonellis PJ, Droz BA, Cosgrove R, O'Farrell LS, Coskun T, Perfield JW 2nd, Bauer S, Wade M, Chouinard TE, Brozinick JT, Adams AC, Samms RJ. Antonellis PJ, et al. Among authors: adams ac. Mol Metab. 2019 Dec;30:131-139. doi: 10.1016/j.molmet.2019.09.006. Epub 2019 Sep 29. Mol Metab. 2019. PMID: 31767164 Free PMC article.
FGF21 requires βklotho to act in vivo.
Adams AC, Cheng CC, Coskun T, Kharitonenkov A. Adams AC, et al. PLoS One. 2012;7(11):e49977. doi: 10.1371/journal.pone.0049977. Epub 2012 Nov 27. PLoS One. 2012. PMID: 23209629 Free PMC article.
121 results