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An FGF21-adiponectin-ceramide axis controls energy expenditure and insulin action in mice.
Holland WL, Adams AC, Brozinick JT, Bui HH, Miyauchi Y, Kusminski CM, Bauer SM, Wade M, Singhal E, Cheng CC, Volk K, Kuo MS, Gordillo R, Kharitonenkov A, Scherer PE. Holland WL, et al. Among authors: brozinick jt. Cell Metab. 2013 May 7;17(5):790-7. doi: 10.1016/j.cmet.2013.03.019. Cell Metab. 2013. PMID: 23663742 Free PMC article.
Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin.
Holland WL, Miller RA, Wang ZV, Sun K, Barth BM, Bui HH, Davis KE, Bikman BT, Halberg N, Rutkowski JM, Wade MR, Tenorio VM, Kuo MS, Brozinick JT, Zhang BB, Birnbaum MJ, Summers SA, Scherer PE. Holland WL, et al. Among authors: brozinick jt. Nat Med. 2011 Jan;17(1):55-63. doi: 10.1038/nm.2277. Epub 2010 Dec 26. Nat Med. 2011. PMID: 21186369 Free PMC article.
The anti-obesity effect of FGF19 does not require UCP1-dependent thermogenesis.
Antonellis PJ, Droz BA, Cosgrove R, O'Farrell LS, Coskun T, Perfield JW 2nd, Bauer S, Wade M, Chouinard TE, Brozinick JT, Adams AC, Samms RJ. Antonellis PJ, et al. Among authors: brozinick jt. Mol Metab. 2019 Dec;30:131-139. doi: 10.1016/j.molmet.2019.09.006. Epub 2019 Sep 29. Mol Metab. 2019. PMID: 31767164 Free PMC article.
Serum sphingolipids: relationships to insulin sensitivity and changes with exercise in humans.
Bergman BC, Brozinick JT, Strauss A, Bacon S, Kerege A, Bui HH, Sanders P, Siddall P, Kuo MS, Perreault L. Bergman BC, et al. Among authors: brozinick jt. Am J Physiol Endocrinol Metab. 2015 Aug 15;309(4):E398-408. doi: 10.1152/ajpendo.00134.2015. Epub 2015 Jun 30. Am J Physiol Endocrinol Metab. 2015. PMID: 26126684 Free PMC article. Clinical Trial.
Genetic ablation of myelin protein zero-like 3 in mice increases energy expenditure, improves glycemic control, and reduces hepatic lipid synthesis.
Czyzyk TA, Andrews JL, Coskun T, Wade MR, Hawkins ED, Lockwood JF, Varga G, Sahr AE, Chen Y, Brozinick JT, Kikly K, Statnick MA. Czyzyk TA, et al. Among authors: brozinick jt. Am J Physiol Endocrinol Metab. 2013 Jul 15;305(2):E282-92. doi: 10.1152/ajpendo.00228.2013. Epub 2013 May 28. Am J Physiol Endocrinol Metab. 2013. PMID: 23715724 Free article.
Tirzepatide induces a thermogenic-like amino acid signature in brown adipose tissue.
Samms RJ, Zhang G, He W, Ilkayeva O, Droz BA, Bauer SM, Stutsman C, Pirro V, Collins KA, Furber EC, Coskun T, Sloop KW, Brozinick JT, Newgard CB. Samms RJ, et al. Among authors: brozinick jt. Mol Metab. 2022 Oct;64:101550. doi: 10.1016/j.molmet.2022.101550. Epub 2022 Jul 31. Mol Metab. 2022. PMID: 35921984 Free PMC article.
Skeletal muscle phosphatidylcholine and phosphatidylethanolamine are related to insulin sensitivity and respond to acute exercise in humans.
Newsom SA, Brozinick JT, Kiseljak-Vassiliades K, Strauss AN, Bacon SD, Kerege AA, Bui HH, Sanders P, Siddall P, Wei T, Thomas M, Kuo MS, Nemkov T, D'Alessandro A, Hansen KC, Perreault L, Bergman BC. Newsom SA, et al. Among authors: brozinick jt. J Appl Physiol (1985). 2016 Jun 1;120(11):1355-63. doi: 10.1152/japplphysiol.00664.2015. Epub 2016 Mar 31. J Appl Physiol (1985). 2016. PMID: 27032901 Free PMC article.
79 results