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Page 1
A multi-site comparison of in vivo safety pharmacology studies conducted to support ICH S7A & B regulatory submissions.
Ewart L, Milne A, Adkins D, Benjamin A, Bialecki R, Chen Y, Ericsson AC, Gardner S, Grant C, Lengel D, Lindgren S, Lowing S, Marks L, Moors J, Oldman K, Pietras M, Prior H, Punton J, Redfern WS, Salmond R, Skinner M, Some M, Stanton A, Swedberg M, Finch J, Valentin JP. Ewart L, et al. Among authors: oldman k. J Pharmacol Toxicol Methods. 2013 Jul-Aug;68(1):30-43. doi: 10.1016/j.vascn.2013.04.008. Epub 2013 May 9. J Pharmacol Toxicol Methods. 2013. PMID: 23665080
Effects of group housing on ECG assessment in conscious cynomolgus monkeys.
Xing G, Lu J, Hu M, Wang S, Zhao L, Zheng W, Schofield J, Oldman K, Adkins D, Yu H, Platz S, Ren J, Skinner M. Xing G, et al. Among authors: oldman k. J Pharmacol Toxicol Methods. 2015 Sep-Oct;75:44-51. doi: 10.1016/j.vascn.2015.05.004. Epub 2015 May 12. J Pharmacol Toxicol Methods. 2015. PMID: 25979821
Effects of group housing on ECG assessment in conscious cynomolgus monkeys.
Xing G, Lu J, Hu M, Wang S, Zhao L, Zheng W, Schofield J, Oldman K, Adkins D, Yu H, Platz S, Ren J, Skinner M. Xing G, et al. Among authors: oldman k. J Pharmacol Toxicol Methods. 2015 Apr 19;73:72-79. doi: 10.1016/j.vascn.2015.04.003. Online ahead of print. J Pharmacol Toxicol Methods. 2015. PMID: 25901446
Preservation of cardiomyocytes from the adult heart.
Abi-Gerges N, Pointon A, Pullen GF, Morton MJ, Oldman KL, Armstrong D, Valentin JP, Pollard CE. Abi-Gerges N, et al. Among authors: oldman kl. J Mol Cell Cardiol. 2013 Nov;64:108-19. doi: 10.1016/j.yjmcc.2013.09.004. Epub 2013 Sep 16. J Mol Cell Cardiol. 2013. PMID: 24051370
Assessment of extracellular field potential and Ca2+ transient signals for early QT/pro-arrhythmia detection using human induced pluripotent stem cell-derived cardiomyocytes.
Abi-Gerges N, Pointon A, Oldman KL, Brown MR, Pilling MA, Sefton CE, Garside H, Pollard CE. Abi-Gerges N, et al. Among authors: oldman kl. J Pharmacol Toxicol Methods. 2017 Jan-Feb;83:1-15. doi: 10.1016/j.vascn.2016.09.001. Epub 2016 Sep 10. J Pharmacol Toxicol Methods. 2017. PMID: 27622857