Nchinda A - Search Results

1

Characterization of angiotensin I-converting enzyme N-domain selectivity using positional-scanning combinatorial libraries of fluorescence resonance energy transfer peptides.

Bersanetti PA, Sabatini RA, Matos BS, Douglas RG, Nchinda A, Juliano MA, Pesquero JB, Sturrock ED, Carmona AK. Bersanetti PA, et al. Among authors: nchinda a. Biol Chem. 2012 Dec;393(12):1547-54. doi: 10.1515/hsz-2012-0170. Biol Chem. 2012. PMID: 23667908

2

Positional-scanning combinatorial libraries of fluorescence resonance energy transfer peptides for defining substrate specificity of the angiotensin I-converting enzyme and development of selective C-domain substrates.

Bersanetti PA, Andrade MC, Casarini DE, Juliano MA, Nchinda AT, Sturrock ED, Juliano L, Carmona AK. Bersanetti PA, et al. Among authors: nchinda at. Biochemistry. 2004 Dec 21;43(50):15729-36. doi: 10.1021/bi048423r. Biochemistry. 2004. PMID: 15595828

3

Novel ketomethylene inhibitors of angiotensin I-converting enzyme (ACE): inhibition and molecular modelling.

Redelinghuys P, Nchinda AT, Chibale K, Sturrock ED. Redelinghuys P, et al. Biol Chem. 2006 Apr;387(4):461-6. doi: 10.1515/BC.2006.061. Biol Chem. 2006. PMID: 16606345

4

Catalytic properties of recombinant dipeptidyl carboxypeptidase from Escherichia coli: a comparative study with angiotensin I-converting enzyme.

Cunha CE, Magliarelli Hde F, Paschoalin T, Nchinda AT, Lima JC, Juliano MA, Paiva PB, Sturrock ED, Travassos LR, Carmona AK. Cunha CE, et al. Among authors: nchinda at. Biol Chem. 2009 Sep;390(9):931-40. doi: 10.1515/BC.2009.105. Biol Chem. 2009. PMID: 19558329

5

Development of domain-selective angiotensin I-converting enzyme inhibitors.

Redelinghuys P, Nchinda AT, Sturrock ED. Redelinghuys P, et al. Ann N Y Acad Sci. 2005 Nov;1056:160-75. doi: 10.1196/annals.1352.035. Ann N Y Acad Sci. 2005. PMID: 16387685

6

Crystal structure of the N domain of human somatic angiotensin I-converting enzyme provides a structural basis for domain-specific inhibitor design.

Corradi HR, Schwager SL, Nchinda AT, Sturrock ED, Acharya KR. Corradi HR, et al. J Mol Biol. 2006 Mar 31;357(3):964-74. doi: 10.1016/j.jmb.2006.01.048. Epub 2006 Jan 31. J Mol Biol. 2006. PMID: 16476442

7

Synthesis and molecular modeling of a lisinopril-tryptophan analogue inhibitor of angiotensin I-converting enzyme.

Nchinda AT, Chibale K, Redelinghuys P, Sturrock ED. Nchinda AT, et al. Bioorg Med Chem Lett. 2006 Sep 1;16(17):4616-9. doi: 10.1016/j.bmcl.2006.06.004. Epub 2006 Jun 19. Bioorg Med Chem Lett. 2006. PMID: 16784843

8

Synthesis of novel keto-ACE analogues as domain-selective angiotensin I-converting enzyme inhibitors.

Nchinda AT, Chibale K, Redelinghuys P, Sturrock ED. Nchinda AT, et al. Bioorg Med Chem Lett. 2006 Sep 1;16(17):4612-5. doi: 10.1016/j.bmcl.2006.06.003. Epub 2006 Jun 19. Bioorg Med Chem Lett. 2006. PMID: 16784850

9

Novel orally active antimalarial thiazoles.

González Cabrera D, Douelle F, Feng TS, Nchinda AT, Younis Y, White KL, Wu Q, Ryan E, Burrows JN, Waterson D, Witty MJ, Wittlin S, Charman SA, Chibale K. González Cabrera D, et al. Among authors: nchinda at. J Med Chem. 2011 Nov 10;54(21):7713-9. doi: 10.1021/jm201108k. Epub 2011 Oct 11. J Med Chem. 2011. PMID: 21966980

10

Structure-activity relationship studies of orally active antimalarial 3,5-substituted 2-aminopyridines.

González Cabrera D, Douelle F, Younis Y, Feng TS, Le Manach C, Nchinda AT, Street LJ, Scheurer C, Kamber J, White KL, Montagnat OD, Ryan E, Katneni K, Zabiulla KM, Joseph JT, Bashyam S, Waterson D, Witty MJ, Charman SA, Wittlin S, Chibale K. González Cabrera D, et al. Among authors: nchinda at. J Med Chem. 2012 Dec 27;55(24):11022-30. doi: 10.1021/jm301476b. Epub 2012 Dec 14. J Med Chem. 2012. PMID: 23189922

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