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Bcl-xL anti-apoptotic network is dispensable for development and maintenance of CML but is required for disease progression where it represents a new therapeutic target.
Harb JG, Neviani P, Chyla BJ, Ellis JJ, Ferenchak GJ, Oaks JJ, Walker CJ, Hokland P, Roy DC, Caligiuri MA, Marcucci G, Huettner CS, Perrotti D. Harb JG, et al. Among authors: caligiuri ma. Leukemia. 2013 Oct;27(10):1996-2005. doi: 10.1038/leu.2013.151. Epub 2013 May 14. Leukemia. 2013. PMID: 23670294 Free PMC article.
BCR-ABL suppresses C/EBPalpha expression through inhibitory action of hnRNP E2.
Perrotti D, Cesi V, Trotta R, Guerzoni C, Santilli G, Campbell K, Iervolino A, Condorelli F, Gambacorti-Passerini C, Caligiuri MA, Calabretta B. Perrotti D, et al. Among authors: caligiuri ma. Nat Genet. 2002 Jan;30(1):48-58. doi: 10.1038/ng791. Epub 2001 Dec 20. Nat Genet. 2002. PMID: 11753385
484 results