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Interleukin-18 activates skeletal muscle AMPK and reduces weight gain and insulin resistance in mice.
Lindegaard B, Matthews VB, Brandt C, Hojman P, Allen TL, Estevez E, Watt MJ, Bruce CR, Mortensen OH, Syberg S, Rudnicka C, Abildgaard J, Pilegaard H, Hidalgo J, Ditlevsen S, Alsted TJ, Madsen AN, Pedersen BK, Febbraio MA. Lindegaard B, et al. Among authors: hojman p. Diabetes. 2013 Sep;62(9):3064-74. doi: 10.2337/db12-1095. Epub 2013 May 13. Diabetes. 2013. PMID: 23670974 Free PMC article.
Brain-derived neurotrophic factor is produced by skeletal muscle cells in response to contraction and enhances fat oxidation via activation of AMP-activated protein kinase.
Matthews VB, Aström MB, Chan MH, Bruce CR, Krabbe KS, Prelovsek O, Akerström T, Yfanti C, Broholm C, Mortensen OH, Penkowa M, Hojman P, Zankari A, Watt MJ, Bruunsgaard H, Pedersen BK, Febbraio MA. Matthews VB, et al. Among authors: hojman p. Diabetologia. 2009 Jul;52(7):1409-18. doi: 10.1007/s00125-009-1364-1. Epub 2009 Apr 22. Diabetologia. 2009. PMID: 19387610
82 results