Ochala J - Search Results

1

Myofilament lattice structure in presence of a skeletal myopathy-related tropomyosin mutation.

Ochala J, Iwamoto H. Ochala J, et al. J Muscle Res Cell Motil. 2013 Aug;34(3-4):171-5. doi: 10.1007/s10974-013-9345-x. Epub 2013 May 18. J Muscle Res Cell Motil. 2013. PMID: 23686574

2

Physical activity impacts resting skeletal muscle myosin conformation and lowers its ATP consumption.

Lewis CTA, Tabrizian L, Nielsen J, Laitila J, Beck TN, Olsen MS, Ognjanovic MM, Aagaard P, Hokken R, Laugesen S, Ingersen A, Andersen JL, Soendenbroe C, Helge JW, Dela F, Larsen S, Sahl RE, Rømer T, Hansen MT, Frandsen J, Suetta C, Ochala J. Lewis CTA, et al. Among authors: ochala j. J Gen Physiol. 2023 Jul 3;155(7):e202213268. doi: 10.1085/jgp.202213268. Epub 2023 May 25. J Gen Physiol. 2023. PMID: 37227464 Free PMC article.

3

Increasing Cardiac Myosin Super-Relaxation With Decreasing Metabolic Demand.

Ochala J, Galán-Arriola C, Veiberg V, Ibanez B. Ochala J, et al. J Am Heart Assoc. 2024 Jun 18;13(12):e035479. doi: 10.1161/JAHA.124.035479. Epub 2024 Jun 11. J Am Heart Assoc. 2024. PMID: 38860415 Free PMC article. No abstract available.

4

Effects of a R133W beta-tropomyosin mutation on regulation of muscle contraction in single human muscle fibres.

Ochala J, Li M, Tajsharghi H, Kimber E, Tulinius M, Oldfors A, Larsson L. Ochala J, et al. J Physiol. 2007 Jun 15;581(Pt 3):1283-92. doi: 10.1113/jphysiol.2007.129759. Epub 2007 Apr 12. J Physiol. 2007. PMID: 17430991 Free PMC article.

5

Defective regulation of contractile function in muscle fibres carrying an E41K beta-tropomyosin mutation.

Ochala J, Li M, Ohlsson M, Oldfors A, Larsson L. Ochala J, et al. J Physiol. 2008 Jun 15;586(12):2993-3004. doi: 10.1113/jphysiol.2008.153650. Epub 2008 Apr 17. J Physiol. 2008. PMID: 18420702 Free PMC article.

6

A myopathy-linked tropomyosin mutation severely alters thin filament conformational changes during activation.

Ochala J, Iwamoto H, Larsson L, Yagi N. Ochala J, et al. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9807-12. doi: 10.1073/pnas.1001733107. Epub 2010 May 10. Proc Natl Acad Sci U S A. 2010. PMID: 20457903 Free PMC article.

7

Disrupted myosin cross-bridge cycling kinetics triggers muscle weakness in nebulin-related myopathy.

Ochala J, Lehtokari VL, Iwamoto H, Li M, Feng HZ, Jin JP, Yagi N, Wallgren-Pettersson C, Pénisson-Besnier I, Larsson L. Ochala J, et al. FASEB J. 2011 Jun;25(6):1903-13. doi: 10.1096/fj.10-176727. Epub 2011 Feb 24. FASEB J. 2011. PMID: 21350120 Free PMC article.

8

A myopathy-related actin mutation increases contractile function.

Lindqvist J, Pénisson-Besnier I, Iwamoto H, Li M, Yagi N, Ochala J. Lindqvist J, et al. Among authors: ochala j. Acta Neuropathol. 2012 May;123(5):739-46. doi: 10.1007/s00401-012-0962-z. Epub 2012 Feb 23. Acta Neuropathol. 2012. PMID: 22358459

9

Congenital myopathy-causing tropomyosin mutations induce thin filament dysfunction via distinct physiological mechanisms.

Ochala J, Gokhin DS, Pénisson-Besnier I, Quijano-Roy S, Monnier N, Lunardi J, Romero NB, Fowler VM. Ochala J, et al. Hum Mol Genet. 2012 Oct 15;21(20):4473-85. doi: 10.1093/hmg/dds289. Epub 2012 Jul 13. Hum Mol Genet. 2012. PMID: 22798622 Free PMC article.

10

Nemaline myopathy-related skeletal muscle α-actin (ACTA1) mutation, Asp286Gly, prevents proper strong myosin binding and triggers muscle weakness.

Ochala J, Ravenscroft G, Laing NG, Nowak KJ. Ochala J, et al. PLoS One. 2012;7(9):e45923. doi: 10.1371/journal.pone.0045923. Epub 2012 Sep 20. PLoS One. 2012. PMID: 23029319 Free PMC article.

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