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321 results

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Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment.
Mathews RJ, Robinson JI, Battellino M, Wong C, Taylor JC; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate (BRAGGSS); Eyre S, Churchman SM, Wilson AG, Isaacs JD, Hyrich K, Barton A, Plant D, Savic S, Cook GP, Sarzi-Puttini P, Emery P, Barrett JH, Morgan AW, McDermott MF. Mathews RJ, et al. Among authors: hyrich k. Ann Rheum Dis. 2014 Jun;73(6):1202-10. doi: 10.1136/annrheumdis-2013-203276. Epub 2013 May 17. Ann Rheum Dis. 2014. PMID: 23687262
Reduction in the incidence of myocardial infarction in patients with rheumatoid arthritis who respond to anti-tumor necrosis factor alpha therapy: results from the British Society for Rheumatology Biologics Register.
Dixon WG, Watson KD, Lunt M, Hyrich KL; British Society for Rheumatology Biologics Register Control Centre Consortium; Silman AJ, Symmons DP; British Society for Rheumatology Biologics Register. Dixon WG, et al. Among authors: hyrich kl. Arthritis Rheum. 2007 Sep;56(9):2905-12. doi: 10.1002/art.22809. Arthritis Rheum. 2007. PMID: 17763428 Free PMC article.
Association of rheumatoid factor and anti-cyclic citrullinated peptide positivity, but not carriage of shared epitope or PTPN22 susceptibility variants, with anti-tumour necrosis factor response in rheumatoid arthritis.
Potter C, Hyrich KL, Tracey A, Lunt M, Plant D, Symmons DP, Thomson W, Worthington J, Emery P, Morgan AW, Wilson AG, Isaacs J, Barton A; BRAGGSS. Potter C, et al. Among authors: hyrich kl. Ann Rheum Dis. 2009 Jan;68(1):69-74. doi: 10.1136/ard.2007.084715. Epub 2008 Mar 28. Ann Rheum Dis. 2009. PMID: 18375541 Free PMC article.
Rates of new-onset psoriasis in patients with rheumatoid arthritis receiving anti-tumour necrosis factor alpha therapy: results from the British Society for Rheumatology Biologics Register.
Harrison MJ, Dixon WG, Watson KD, King Y, Groves R, Hyrich KL, Symmons DP; British Society for Rheumatology Biologics Register Control Centre Consortium; BSRBR. Harrison MJ, et al. Among authors: hyrich kl. Ann Rheum Dis. 2009 Feb;68(2):209-15. doi: 10.1136/ard.2007.087288. Epub 2008 Apr 2. Ann Rheum Dis. 2009. PMID: 18385277 Free PMC article.
Different methods of balancing covariates leading to different effect estimates in the presence of effect modification.
Lunt M, Solomon D, Rothman K, Glynn R, Hyrich K, Symmons DP, Stürmer T; British Society for Rheumatology Biologics Register; British Society for Rheumatology Biologics Register Control Centre Consortium. Lunt M, et al. Among authors: hyrich k. Am J Epidemiol. 2009 Apr 1;169(7):909-17. doi: 10.1093/aje/kwn391. Epub 2009 Jan 19. Am J Epidemiol. 2009. PMID: 19153216 Free PMC article.
Investigation of genetic variants within candidate genes of the TNFRSF1B signalling pathway on the response to anti-TNF agents in a UK cohort of rheumatoid arthritis patients.
Bowes JD, Potter C, Gibbons LJ, Hyrich K, Plant D, Morgan AW, Wilson AG, Isaacs JD, Worthington J, Barton A; BRAGGSS. Bowes JD, et al. Among authors: hyrich k. Pharmacogenet Genomics. 2009 Apr;19(4):319-23. doi: 10.1097/FPC.0b013e328328d51f. Pharmacogenet Genomics. 2009. PMID: 19262425
Benefit of anti-TNF therapy in rheumatoid arthritis patients with moderate disease activity.
Hyrich KL, Deighton C, Watson KD; BSRBR Control Centre Consortium; Symmons DP, Lunt M; British Society for Rheumatology Biologics Register. Hyrich KL, et al. Rheumatology (Oxford). 2009 Oct;48(10):1323-7. doi: 10.1093/rheumatology/kep242. Epub 2009 Aug 25. Rheumatology (Oxford). 2009. PMID: 19706737 Free PMC article. Clinical Trial.
321 results