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Phosphatidylinositol-4,5-biphosphate-dependent rearrangement of TRPV4 cytosolic tails enables channel activation by physiological stimuli.
Garcia-Elias A, Mrkonjic S, Pardo-Pastor C, Inada H, Hellmich UA, Rubio-Moscardó F, Plata C, Gaudet R, Vicente R, Valverde MA. Garcia-Elias A, et al. Among authors: plata c. Proc Natl Acad Sci U S A. 2013 Jun 4;110(23):9553-8. doi: 10.1073/pnas.1220231110. Epub 2013 May 20. Proc Natl Acad Sci U S A. 2013. PMID: 23690576 Free PMC article.
The progesterone receptor regulates the expression of TRPV4 channel.
Jung C, Fandos C, Lorenzo IM, Plata C, Fernandes J, Gené GG, Vázquez E, Valverde MA. Jung C, et al. Among authors: plata c. Pflugers Arch. 2009 Nov;459(1):105-13. doi: 10.1007/s00424-009-0706-7. Epub 2009 Aug 23. Pflugers Arch. 2009. PMID: 19701771
A mutation in the first intracellular loop of CACNA1A prevents P/Q channel modulation by SNARE proteins and lowers exocytosis.
Serra SA, Cuenca-León E, Llobet A, Rubio-Moscardo F, Plata C, Carreño O, Fernàndez-Castillo N, Corominas R, Valverde MA, Macaya A, Cormand B, Fernández-Fernández JM. Serra SA, et al. Among authors: plata c. Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1672-7. doi: 10.1073/pnas.0908359107. Epub 2010 Jan 8. Proc Natl Acad Sci U S A. 2010. PMID: 20080591 Free PMC article.
TRPV4 activation triggers protective responses to bacterial lipopolysaccharides in airway epithelial cells.
Alpizar YA, Boonen B, Sanchez A, Jung C, López-Requena A, Naert R, Steelant B, Luyts K, Plata C, De Vooght V, Vanoirbeek JAJ, Meseguer VM, Voets T, Alvarez JL, Hellings PW, Hoet PHM, Nemery B, Valverde MA, Talavera K. Alpizar YA, et al. Among authors: plata c. Nat Commun. 2017 Oct 20;8(1):1059. doi: 10.1038/s41467-017-01201-3. Nat Commun. 2017. PMID: 29057902 Free PMC article.
In vitro and in vivo evidence for an inflammatory role of the calcium channel TRPV4 in lung epithelium: Potential involvement in cystic fibrosis.
Henry CO, Dalloneau E, Pérez-Berezo MT, Plata C, Wu Y, Guillon A, Morello E, Aimar RF, Potier-Cartereau M, Esnard F, Coraux C, Börnchen C, Kiefmann R, Vandier C, Touqui L, Valverde MA, Cenac N, Si-Tahar M. Henry CO, et al. Among authors: plata c. Am J Physiol Lung Cell Mol Physiol. 2016 Sep 1;311(3):L664-75. doi: 10.1152/ajplung.00442.2015. Epub 2016 Aug 5. Am J Physiol Lung Cell Mol Physiol. 2016. PMID: 27496898 Free article.
Rare variants in calcium homeostasis modulator 1 (CALHM1) found in early onset Alzheimer's disease patients alter calcium homeostasis.
Rubio-Moscardo F, Setó-Salvia N, Pera M, Bosch-Morató M, Plata C, Belbin O, Gené G, Dols-Icardo O, Ingelsson M, Helisalmi S, Soininen H, Hiltunen M, Giedraitis V, Lannfelt L, Frank A, Bullido MJ, Combarros O, Sánchez-Juan P, Boada M, Tárraga L, Pastor P, Pérez-Tur J, Baquero M, Molinuevo JL, Sánchez-Valle R, Fuentes-Prior P, Fortea J, Blesa R, Muñoz FJ, Lleó A, Valverde MA, Clarimón J. Rubio-Moscardo F, et al. Among authors: plata c. PLoS One. 2013 Sep 17;8(9):e74203. doi: 10.1371/journal.pone.0074203. eCollection 2013. PLoS One. 2013. PMID: 24069280 Free PMC article.
Constitutive Cyclin O deficiency results in penetrant hydrocephalus, impaired growth and infertility.
Núnez-Ollé M, Jung C, Terré B, Balsiger NA, Plata C, Roset R, Pardo-Pastor C, Garrido M, Rojas S, Alameda F, Lloreta J, Martín-Caballero J, Flores JM, Stracker TH, Valverde MA, Muñoz FJ, Gil-Gómez G. Núnez-Ollé M, et al. Among authors: plata c. Oncotarget. 2017 Oct 12;8(59):99261-99273. doi: 10.18632/oncotarget.21818. eCollection 2017 Nov 21. Oncotarget. 2017. PMID: 29245899 Free PMC article.
92 results