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Small molecule antagonists of the sigma-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo.
Spruce BA, Campbell LA, McTavish N, Cooper MA, Appleyard MV, O'Neill M, Howie J, Samson J, Watt S, Murray K, McLean D, Leslie NR, Safrany ST, Ferguson MJ, Peters JA, Prescott AR, Box G, Hayes A, Nutley B, Raynaud F, Downes CP, Lambert JJ, Thompson AM, Eccles S. Spruce BA, et al. Cancer Res. 2004 Jul 15;64(14):4875-86. doi: 10.1158/0008-5472.CAN-03-3180. Cancer Res. 2004. PMID: 15256458
Decoding the neural mechanisms of human tool use.
Gallivan JP, McLean DA, Valyear KF, Culham JC. Gallivan JP, et al. Among authors: mclean da. Elife. 2013 May 28;2:e00425. doi: 10.7554/eLife.00425. Elife. 2013. PMID: 23741616 Free PMC article.
37 results