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Brain metastatic outgrowth and osimertinib resistance are potentiated by RhoA in EGFR-mutant lung cancer.
Adua SJ, Arnal-Estapé A, Zhao M, Qi B, Liu ZZ, Kravitz C, Hulme H, Strittmatter N, López-Giráldez F, Chande S, Albert AE, Melnick MA, Hu B, Politi K, Chiang V, Colclough N, Goodwin RJA, Cross D, Smith P, Nguyen DX. Adua SJ, et al. Among authors: liu zz. Nat Commun. 2022 Dec 12;13(1):7690. doi: 10.1038/s41467-022-34889-z. Nat Commun. 2022. PMID: 36509758 Free PMC article.
ASCL1 Drives Tolerance to Osimertinib in EGFR Mutant Lung Cancer in Permissive Cellular Contexts.
Hu B, Wiesehöfer M, de Miguel FJ, Liu Z, Chan LH, Choi J, Melnick MA, Arnal Estape A, Walther Z, Zhao D, Lopez-Giraldez F, Wurtz A, Cai G, Fan R, Gettinger S, Xiao A, Yan Q, Homer R, Nguyen DX, Politi K. Hu B, et al. Among authors: liu z. Cancer Res. 2024 Apr 15;84(8):1303-1319. doi: 10.1158/0008-5472.CAN-23-0438. Cancer Res. 2024. PMID: 38359163 Free PMC article.
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