Titz A - Search Results

1

Discovery of two classes of potent glycomimetic inhibitors of Pseudomonas aeruginosa LecB with distinct binding modes.

Hauck D, Joachim I, Frommeyer B, Varrot A, Philipp B, Möller HM, Imberty A, Exner TE, Titz A. Hauck D, et al. Among authors: titz a. ACS Chem Biol. 2013 Aug 16;8(8):1775-84. doi: 10.1021/cb400371r. Epub 2013 Jun 28. ACS Chem Biol. 2013. PMID: 23719508

2

New approaches to control infections: anti-biofilm strategies against gram-negative bacteria.

Sommer R, Joachim I, Wagner S, Titz A. Sommer R, et al. Among authors: titz a. Chimia (Aarau). 2013;67(4):286-90. doi: 10.2533/chimia.2013.286. Chimia (Aarau). 2013. PMID: 23967708 Free article. Review.

3

Methylated glycans as conserved targets of animal and fungal innate defense.

Wohlschlager T, Butschi A, Grassi P, Sutov G, Gauss R, Hauck D, Schmieder SS, Knobel M, Titz A, Dell A, Haslam SM, Hengartner MO, Aebi M, Künzler M. Wohlschlager T, et al. Among authors: titz a. Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):E2787-96. doi: 10.1073/pnas.1401176111. Epub 2014 May 30. Proc Natl Acad Sci U S A. 2014. PMID: 24879441 Free PMC article.

4

A biophysical study with carbohydrate derivatives explains the molecular basis of monosaccharide selectivity of the Pseudomonas aeruginosa lectin LecB.

Sommer R, Exner TE, Titz A. Sommer R, et al. Among authors: titz a. PLoS One. 2014 Nov 21;9(11):e112822. doi: 10.1371/journal.pone.0112822. eCollection 2014. PLoS One. 2014. PMID: 25415418 Free PMC article.

5

Synthesis of mannoheptose derivatives and their evaluation as inhibitors of the lectin LecB from the opportunistic pathogen Pseudomonas aeruginosa.

Hofmann A, Sommer R, Hauck D, Stifel J, Göttker-Schnetmann I, Titz A. Hofmann A, et al. Among authors: titz a. Carbohydr Res. 2015 Aug 14;412:34-42. doi: 10.1016/j.carres.2015.04.010. Epub 2015 May 5. Carbohydr Res. 2015. PMID: 26004349

6

Cinnamide Derivatives of d-Mannose as Inhibitors of the Bacterial Virulence Factor LecB from Pseudomonas aeruginosa.

Sommer R, Hauck D, Varrot A, Wagner S, Audfray A, Prestel A, Möller HM, Imberty A, Titz A. Sommer R, et al. Among authors: titz a. ChemistryOpen. 2015 Oct 13;4(6):756-67. doi: 10.1002/open.201500162. eCollection 2015 Dec. ChemistryOpen. 2015. PMID: 27308201 Free PMC article.

7

Development and optimization of a competitive binding assay for the galactophilic low affinity lectin LecA from Pseudomonas aeruginosa.

Joachim I, Rikker S, Hauck D, Ponader D, Boden S, Sommer R, Hartmann L, Titz A. Joachim I, et al. Among authors: titz a. Org Biomol Chem. 2016 Aug 16;14(33):7933-48. doi: 10.1039/c6ob01313a. Org Biomol Chem. 2016. PMID: 27488655

8

O-Alkylated heavy atom carbohydrate probes for protein X-ray crystallography: Studies towards the synthesis of methyl 2-O-methyl-L-selenofucopyranoside.

Sommer R, Hauck D, Varrot A, Imberty A, Künzler M, Titz A. Sommer R, et al. Among authors: titz a. Beilstein J Org Chem. 2016 Dec 22;12:2828-2833. doi: 10.3762/bjoc.12.282. eCollection 2016. Beilstein J Org Chem. 2016. PMID: 28144356 Free PMC article.

9

Photoswitchable Janus glycodendrimer micelles as multivalent inhibitors of LecA and LecB from Pseudomonas aeruginosa.

Hu Y, Beshr G, Garvey CJ, Tabor RF, Titz A, Wilkinson BL. Hu Y, et al. Among authors: titz a. Colloids Surf B Biointerfaces. 2017 Nov 1;159:605-612. doi: 10.1016/j.colsurfb.2017.08.016. Epub 2017 Aug 16. Colloids Surf B Biointerfaces. 2017. PMID: 28858663

10

Covalent Lectin Inhibition and Application in Bacterial Biofilm Imaging.

Wagner S, Hauck D, Hoffmann M, Sommer R, Joachim I, Müller R, Imberty A, Varrot A, Titz A. Wagner S, et al. Among authors: titz a. Angew Chem Int Ed Engl. 2017 Dec 22;56(52):16559-16564. doi: 10.1002/anie.201709368. Epub 2017 Nov 28. Angew Chem Int Ed Engl. 2017. PMID: 28960731 Free PMC article.

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