Vander Jagt DL - Search Results

1

Evaluation of LDH-A and glutaminase inhibition in vivo by hyperpolarized 13C-pyruvate magnetic resonance spectroscopy of tumors.

Dutta P, Le A, Vander Jagt DL, Tsukamoto T, Martinez GV, Dang CV, Gillies RJ. Dutta P, et al. Among authors: vander jagt dl. Cancer Res. 2013 Jul 15;73(14):4190-5. doi: 10.1158/0008-5472.CAN-13-0465. Epub 2013 May 30. Cancer Res. 2013. PMID: 23722553 Free PMC article.

2

Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression.

Le A, Cooper CR, Gouw AM, Dinavahi R, Maitra A, Deck LM, Royer RE, Vander Jagt DL, Semenza GL, Dang CV. Le A, et al. Among authors: vander jagt dl. Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):2037-42. doi: 10.1073/pnas.0914433107. Epub 2010 Jan 19. Proc Natl Acad Sci U S A. 2010. PMID: 20133848 Free PMC article.

3

17-beta-Hydroxysteroid dehydrogenase type 1: computational design of active site inhibitors targeted to the Rossmann fold.

Brown WM, Metzger LE, Barlow JP, Hunsaker LA, Deck LM, Royer RE, Vander Jagt DL. Brown WM, et al. Among authors: vander jagt dl. Chem Biol Interact. 2003 Feb 1;143-144:481-91. doi: 10.1016/s0009-2797(02)00184-9. Chem Biol Interact. 2003. PMID: 12604234

4

The curcumin analog ca27 down-regulates androgen receptor through an oxidative stress mediated mechanism in human prostate cancer cells.

Fajardo AM, MacKenzie DA, Ji M, Deck LM, Vander Jagt DL, Thompson TA, Bisoffi M. Fajardo AM, et al. Among authors: vander jagt dl. Prostate. 2012 May 1;72(6):612-25. doi: 10.1002/pros.21464. Epub 2011 Jul 27. Prostate. 2012. PMID: 21796654 Free PMC article.

5

Selective active site inhibitors of human lactate dehydrogenases A4, B4, and C4.

Yu Y, Deck JA, Hunsaker LA, Deck LM, Royer RE, Goldberg E, Vander Jagt DL. Yu Y, et al. Among authors: vander jagt dl. Biochem Pharmacol. 2001 Jul 1;62(1):81-9. doi: 10.1016/s0006-2952(01)00636-0. Biochem Pharmacol. 2001. PMID: 11377399

6

Substrate and cofactor specificity and selective inhibition of lactate dehydrogenase from the malarial parasite P. falciparum.

Gomez MS, Piper RC, Hunsaker LA, Royer RE, Deck LM, Makler MT, Vander Jagt DL. Gomez MS, et al. Among authors: vander jagt dl. Mol Biochem Parasitol. 1997 Dec 1;90(1):235-46. doi: 10.1016/s0166-6851(97)00140-0. Mol Biochem Parasitol. 1997. PMID: 9497046

7

Selective inhibitors of human lactate dehydrogenases and lactate dehydrogenase from the malarial parasite Plasmodium falciparum.

Deck LM, Royer RE, Chamblee BB, Hernandez VM, Malone RR, Torres JE, Hunsaker LA, Piper RC, Makler MT, Vander Jagt DL. Deck LM, et al. Among authors: vander jagt dl. J Med Chem. 1998 Sep 24;41(20):3879-87. doi: 10.1021/jm980334n. J Med Chem. 1998. PMID: 9748363

8

The kinetic properties and sensitivities to inhibitors of lactate dehydrogenases (LDH1 and LDH2) from Toxoplasma gondii: comparisons with pLDH from Plasmodium falciparum.

Dando C, Schroeder ER, Hunsaker LA, Deck LM, Royer RE, Zhou X, Parmley SF, Vander Jagt DL. Dando C, et al. Among authors: vander jagt dl. Mol Biochem Parasitol. 2001 Nov;118(1):23-32. doi: 10.1016/s0166-6851(01)00360-7. Mol Biochem Parasitol. 2001. PMID: 11704270

9

Comparative structural analysis and kinetic properties of lactate dehydrogenases from the four species of human malarial parasites.

Brown WM, Yowell CA, Hoard A, Vander Jagt TA, Hunsaker LA, Deck LM, Royer RE, Piper RC, Dame JB, Makler MT, Vander Jagt DL. Brown WM, et al. Among authors: vander jagt ta, vander jagt dl. Biochemistry. 2004 May 25;43(20):6219-29. doi: 10.1021/bi049892w. Biochemistry. 2004. PMID: 15147206

10

Activation of NFkappaB is inhibited by curcumin and related enones.

Weber WM, Hunsaker LA, Roybal CN, Bobrovnikova-Marjon EV, Abcouwer SF, Royer RE, Deck LM, Vander Jagt DL. Weber WM, et al. Among authors: vander jagt dl. Bioorg Med Chem. 2006 Apr 1;14(7):2450-61. doi: 10.1016/j.bmc.2005.11.035. Epub 2005 Dec 7. Bioorg Med Chem. 2006. PMID: 16338138

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