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Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy.
Jordanova A, Irobi J, Thomas FP, Van Dijck P, Meerschaert K, Dewil M, Dierick I, Jacobs A, De Vriendt E, Guergueltcheva V, Rao CV, Tournev I, Gondim FA, D'Hooghe M, Van Gerwen V, Callaerts P, Van Den Bosch L, Timmermans JP, Robberecht W, Gettemans J, Thevelein JM, De Jonghe P, Kremensky I, Timmerman V. Jordanova A, et al. Among authors: timmermans jp. Nat Genet. 2006 Feb;38(2):197-202. doi: 10.1038/ng1727. Epub 2006 Jan 22. Nat Genet. 2006. PMID: 16429158 Free article.
Mutant HSPB8 causes motor neuron-specific neurite degeneration.
Irobi J, Almeida-Souza L, Asselbergh B, De Winter V, Goethals S, Dierick I, Krishnan J, Timmermans JP, Robberecht W, De Jonghe P, Van Den Bosch L, Janssens S, Timmerman V. Irobi J, et al. Among authors: timmermans jp. Hum Mol Genet. 2010 Aug 15;19(16):3254-65. doi: 10.1093/hmg/ddq234. Epub 2010 Jun 10. Hum Mol Genet. 2010. PMID: 20538880 Free PMC article.
Small heat-shock protein HSPB1 mutants stabilize microtubules in Charcot-Marie-Tooth neuropathy.
Almeida-Souza L, Asselbergh B, d'Ydewalle C, Moonens K, Goethals S, de Winter V, Azmi A, Irobi J, Timmermans JP, Gevaert K, Remaut H, Van Den Bosch L, Timmerman V, Janssens S. Almeida-Souza L, et al. Among authors: timmermans jp. J Neurosci. 2011 Oct 26;31(43):15320-8. doi: 10.1523/JNEUROSCI.3266-11.2011. J Neurosci. 2011. PMID: 22031878 Free PMC article.
Systematic Quantification of Synapses in Primary Neuronal Culture.
Verstraelen P, Garcia-Diaz Barriga G, Verschuuren M, Asselbergh B, Nuydens R, Larsen PH, Timmermans JP, De Vos WH. Verstraelen P, et al. Among authors: timmermans jp. iScience. 2020 Sep 7;23(9):101542. doi: 10.1016/j.isci.2020.101542. eCollection 2020 Sep 25. iScience. 2020. PMID: 33083769 Free PMC article.
Microglial derived extracellular vesicles activate autophagy and mediate multi-target signaling to maintain cellular homeostasis.
Van den Broek B, Pintelon I, Hamad I, Kessels S, Haidar M, Hellings N, Hendriks JJA, Kleinewietfeld M, Brône B, Timmerman V, Timmermans JP, Somers V, Michiels L, Irobi J. Van den Broek B, et al. Among authors: timmermans jp. J Extracell Vesicles. 2020 Nov;10(1):e12022. doi: 10.1002/jev2.12022. Epub 2020 Nov 25. J Extracell Vesicles. 2020. PMID: 33708355 Free PMC article.
Oligodendroglia-derived extracellular vesicles activate autophagy via LC3B/BAG3 to protect against oxidative stress with an enhanced effect for HSPB8 enriched vesicles.
Van den Broek B, Wuyts C, Sisto A, Pintelon I, Timmermans JP, Somers V, Timmerman V, Hellings N, Irobi J. Van den Broek B, et al. Among authors: timmermans jp. Cell Commun Signal. 2022 May 5;20(1):58. doi: 10.1186/s12964-022-00863-x. Cell Commun Signal. 2022. PMID: 35513867 Free PMC article.
361 results