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Ophiobolin A, a sesterterpenoid fungal phytotoxin, displays higher in vitro growth-inhibitory effects in mammalian than in plant cells and displays in vivo antitumor activity.
Bury M, Novo-Uzal E, Andolfi A, Cimini S, Wauthoz N, Heffeter P, Lallemand B, Avolio F, Delporte C, Cimmino A, Dubois J, Van Antwerpen P, Zonno MC, Vurro M, Poumay Y, Berger W, Evidente A, De Gara L, Kiss R, Locato V. Bury M, et al. Among authors: kiss r. Int J Oncol. 2013 Aug;43(2):575-85. doi: 10.3892/ijo.2013.1979. Epub 2013 Jun 10. Int J Oncol. 2013. PMID: 23754298
In vitro anticancer activity, toxicity and structure-activity relationships of phyllostictine A, a natural oxazatricycloalkenone produced by the fungus Phyllosticta cirsii.
Le Calvé B, Lallemand B, Perrone C, Lenglet G, Depauw S, Van Goietsenoven G, Bury M, Vurro M, Herphelin F, Andolfi A, Zonno MC, Mathieu V, Dufrasne F, Van Antwerpen P, Poumay Y, David-Cordonnier MH, Evidente A, Kiss R. Le Calvé B, et al. Among authors: kiss r. Toxicol Appl Pharmacol. 2011 Jul 1;254(1):8-17. doi: 10.1016/j.taap.2011.03.027. Epub 2011 Apr 12. Toxicol Appl Pharmacol. 2011. PMID: 21504755
Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
Lamoral-Theys D, Andolfi A, Van Goietsenoven G, Cimmino A, Le Calvé B, Wauthoz N, Mégalizzi V, Gras T, Bruyère C, Dubois J, Mathieu V, Kornienko A, Kiss R, Evidente A. Lamoral-Theys D, et al. Among authors: kiss r. J Med Chem. 2009 Oct 22;52(20):6244-56. doi: 10.1021/jm901031h. J Med Chem. 2009. PMID: 19788245 Free PMC article.
Targeting of eEF1A with Amaryllidaceae isocarbostyrils as a strategy to combat melanomas.
Van Goietsenoven G, Hutton J, Becker JP, Lallemand B, Robert F, Lefranc F, Pirker C, Vandenbussche G, Van Antwerpen P, Evidente A, Berger W, Prévost M, Pelletier J, Kiss R, Kinzy TG, Kornienko A, Mathieu V. Van Goietsenoven G, et al. Among authors: kiss r. FASEB J. 2010 Nov;24(11):4575-84. doi: 10.1096/fj.10-162263. Epub 2010 Jul 19. FASEB J. 2010. PMID: 20643906 Free PMC article.
1,011 results