Thomas D - Search Results

1

Targeting acute myeloid leukemia by dual inhibition of PI3K signaling and Cdk9-mediated Mcl-1 transcription.

Thomas D, Powell JA, Vergez F, Segal DH, Nguyen NY, Baker A, Teh TC, Barry EF, Sarry JE, Lee EM, Nero TL, Jabbour AM, Pomilio G, Green BD, Manenti S, Glaser SP, Parker MW, Lopez AF, Ekert PG, Lock RB, Huang DC, Nilsson SK, Récher C, Wei AH, Guthridge MA. Thomas D, et al. Blood. 2013 Aug 1;122(5):738-48. doi: 10.1182/blood-2012-08-447441. Epub 2013 Jun 17. Blood. 2013. PMID: 23775716 Free article.

2

Mechanism of activation of the GM-CSF, IL-3, and IL-5 family of receptors.

Guthridge MA, Stomski FC, Thomas D, Woodcock JM, Bagley CJ, Berndt MC, Lopez AF. Guthridge MA, et al. Among authors: thomas d. Stem Cells. 1998;16(5):301-13. doi: 10.1002/stem.160301. Stem Cells. 1998. PMID: 9766809 Review.

3

Identification of a 14-3-3 binding sequence in the common beta chain of the granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3), and IL-5 receptors that is serine-phosphorylated by GM-CSF.

Stomski FC, Dottore M, Winnall W, Guthridge MA, Woodcock J, Bagley CJ, Thomas DT, Andrews RK, Berndt MC, Lopez AF. Stomski FC, et al. Among authors: thomas dt. Blood. 1999 Sep 15;94(6):1933-42. Blood. 1999. PMID: 10477722 Free article.

4

Regulation of haematopoiesis by growth factors - emerging insights and therapies.

Thomas D, Vadas M, Lopez A. Thomas D, et al. Expert Opin Biol Ther. 2004 Jun;4(6):869-79. doi: 10.1517/14712598.4.6.869. Expert Opin Biol Ther. 2004. PMID: 15174969 Review.

5

14-3-3 protein signaling in development and growth factor responses.

Thomas D, Guthridge M, Woodcock J, Lopez A. Thomas D, et al. Curr Top Dev Biol. 2005;67:285-303. doi: 10.1016/S0070-2153(05)67009-3. Curr Top Dev Biol. 2005. PMID: 15949538 Review.

6

Growth factor pleiotropy is controlled by a receptor Tyr/Ser motif that acts as a binary switch.

Guthridge MA, Powell JA, Barry EF, Stomski FC, McClure BJ, Ramshaw H, Felquer FA, Dottore M, Thomas DT, To B, Begley CG, Lopez AF. Guthridge MA, et al. EMBO J. 2006 Feb 8;25(3):479-89. doi: 10.1038/sj.emboj.7600948. Epub 2006 Jan 26. EMBO J. 2006. PMID: 16437163 Free PMC article.

7

The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease.

Hercus TR, Thomas D, Guthridge MA, Ekert PG, King-Scott J, Parker MW, Lopez AF. Hercus TR, et al. Among authors: thomas d. Blood. 2009 Aug 13;114(7):1289-98. doi: 10.1182/blood-2008-12-164004. Epub 2009 May 12. Blood. 2009. PMID: 19436055 Free PMC article. Review.

8

Monoclonal antibody-mediated targeting of CD123, IL-3 receptor alpha chain, eliminates human acute myeloid leukemic stem cells.

Jin L, Lee EM, Ramshaw HS, Busfield SJ, Peoppl AG, Wilkinson L, Guthridge MA, Thomas D, Barry EF, Boyd A, Gearing DP, Vairo G, Lopez AF, Dick JE, Lock RB. Jin L, et al. Among authors: thomas d. Cell Stem Cell. 2009 Jul 2;5(1):31-42. doi: 10.1016/j.stem.2009.04.018. Cell Stem Cell. 2009. PMID: 19570512 Free article.

9

Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML.

Powell JA, Thomas D, Barry EF, Kok CH, McClure BJ, Tsykin A, To LB, Brown A, Lewis ID, Herbert K, Goodall GJ, Speed TP, Asou N, Jacob B, Osato M, Haylock DN, Nilsson SK, D'Andrea RJ, Lopez AF, Guthridge MA. Powell JA, et al. Among authors: thomas d, d andrea rj. Blood. 2009 Nov 26;114(23):4859-70. doi: 10.1182/blood-2009-02-204818. Epub 2009 Oct 5. Blood. 2009. PMID: 19805619 Free article.

10

Molecular basis of cytokine receptor activation.

Lopez AF, Hercus TR, Ekert P, Littler DR, Guthridge M, Thomas D, Ramshaw HS, Stomski F, Perugini M, D'Andrea R, Grimbaldeston M, Parker MW. Lopez AF, et al. Among authors: thomas d, d andrea r. IUBMB Life. 2010 Jul;62(7):509-18. doi: 10.1002/iub.350. IUBMB Life. 2010. PMID: 20540154 Free article. Review.

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