Lerner M - Search Results

1

CDK-mediated activation of the SCF(FBXO) (28) ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer.

Cepeda D, Ng HF, Sharifi HR, Mahmoudi S, Cerrato VS, Fredlund E, Magnusson K, Nilsson H, Malyukova A, Rantala J, Klevebring D, Viñals F, Bhaskaran N, Zakaria SM, Rahmanto AS, Grotegut S, Nielsen ML, Szigyarto CA, Sun D, Lerner M, Navani S, Widschwendter M, Uhlén M, Jirström K, Pontén F, Wohlschlegel J, Grandér D, Spruck C, Larsson LG, Sangfelt O. Cepeda D, et al. Among authors: lerner m. EMBO Mol Med. 2013 Jul;5(7):1067-86. doi: 10.1002/emmm.201202341. Epub 2013 Jun 14. EMBO Mol Med. 2013. PMID: 23776131 Free PMC article.

2

The RBCC gene RFP2 (Leu5) encodes a novel transmembrane E3 ubiquitin ligase involved in ERAD.

Lerner M, Corcoran M, Cepeda D, Nielsen ML, Zubarev R, Pontén F, Uhlén M, Hober S, Grandér D, Sangfelt O. Lerner M, et al. Mol Biol Cell. 2007 May;18(5):1670-82. doi: 10.1091/mbc.e06-03-0248. Epub 2007 Feb 21. Mol Biol Cell. 2007. PMID: 17314412 Free PMC article.

3

MiRNA-27a controls FBW7/hCDC4-dependent cyclin E degradation and cell cycle progression.

Lerner M, Lundgren J, Akhoondi S, Jahn A, Ng HF, Akbari Moqadam F, Oude Vrielink JA, Agami R, Den Boer ML, Grandér D, Sangfelt O. Lerner M, et al. Cell Cycle. 2011 Jul 1;10(13):2172-83. doi: 10.4161/cc.10.13.16248. Epub 2011 Jul 1. Cell Cycle. 2011. PMID: 21597324

4

MiR-200c regulates Noxa expression and sensitivity to proteasomal inhibitors.

Lerner M, Haneklaus M, Harada M, Grandér D. Lerner M, et al. PLoS One. 2012;7(5):e36490. doi: 10.1371/journal.pone.0036490. Epub 2012 May 15. PLoS One. 2012. PMID: 22615771 Free PMC article.

5

DLEU2, frequently deleted in malignancy, functions as a critical host gene of the cell cycle inhibitory microRNAs miR-15a and miR-16-1.

Lerner M, Harada M, Lovén J, Castro J, Davis Z, Oscier D, Henriksson M, Sangfelt O, Grandér D, Corcoran MM. Lerner M, et al. Exp Cell Res. 2009 Oct 15;315(17):2941-52. doi: 10.1016/j.yexcr.2009.07.001. Epub 2009 Jul 8. Exp Cell Res. 2009. PMID: 19591824

6

Expression of the p53 target Wig-1 is associated with HPV status and patient survival in cervical carcinoma.

Xu LD, Muller S, Thoppe SR, Hellborg F, Kanter L, Lerner M, Zheng B, Lagercrantz SB, Grandér D, Wallin KL, Wiman KG, Larsson C, Andersson S. Xu LD, et al. Among authors: lerner m. PLoS One. 2014 Nov 7;9(11):e111125. doi: 10.1371/journal.pone.0111125. eCollection 2014. PLoS One. 2014. PMID: 25379706 Free PMC article.

7

Disruption of a novel ectodermal neural cortex 1 antisense gene, ENC-1AS and identification of ENC-1 overexpression in hairy cell leukemia.

Hammarsund M, Lerner M, Zhu C, Merup M, Jansson M, Gahrton G, Kluin-Nelemans H, Einhorn S, Grandér D, Sangfelt O, Corcoran M. Hammarsund M, et al. Among authors: lerner m. Hum Mol Genet. 2004 Dec 1;13(23):2925-36. doi: 10.1093/hmg/ddh315. Epub 2004 Sep 30. Hum Mol Genet. 2004. PMID: 15459180

8

DLEU2 encodes an antisense RNA for the putative bicistronic RFP2/LEU5 gene in humans and mouse.

Corcoran MM, Hammarsund M, Zhu C, Lerner M, Kapanadze B, Wilson B, Larsson C, Forsberg L, Ibbotson RE, Einhorn S, Oscier DG, Grandér D, Sangfelt O. Corcoran MM, et al. Among authors: lerner m. Genes Chromosomes Cancer. 2004 Aug;40(4):285-97. doi: 10.1002/gcc.20046. Genes Chromosomes Cancer. 2004. PMID: 15188451

9

Loss of chromosome 13q is a frequently acquired event in genetic progression of soft tissue sarcomas in the abdominal cavity.

Weng WH, Lerner M, Grandér D, Ahlén J, Villablanca A, Pang ST, Wejde J, Lui WO, Larsson C. Weng WH, et al. Among authors: lerner m. Int J Oncol. 2005 Jan;26(1):5-16. Int J Oncol. 2005. PMID: 15586219

10

Targeting autophagy by small molecule inhibitors of vacuolar protein sorting 34 (Vps34) improves the sensitivity of breast cancer cells to Sunitinib.

Dyczynski M, Yu Y, Otrocka M, Parpal S, Braga T, Henley AB, Zazzi H, Lerner M, Wennerberg K, Viklund J, Martinsson J, Grandér D, De Milito A, Pokrovskaja Tamm K. Dyczynski M, et al. Among authors: lerner m. Cancer Lett. 2018 Oct 28;435:32-43. doi: 10.1016/j.canlet.2018.07.028. Epub 2018 Jul 25. Cancer Lett. 2018. PMID: 30055290 Free article.

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