Nohmi T - Search Results

1

DNA polymerase κ-dependent DNA synthesis at stalled replication forks is important for CHK1 activation.

Bétous R, Pillaire MJ, Pierini L, van der Laan S, Recolin B, Ohl-Séguy E, Guo C, Niimi N, Grúz P, Nohmi T, Friedberg E, Cazaux C, Maiorano D, Hoffmann JS. Bétous R, et al. Among authors: nohmi t. EMBO J. 2013 Jul 31;32(15):2172-85. doi: 10.1038/emboj.2013.148. Epub 2013 Jun 25. EMBO J. 2013. PMID: 23799366 Free PMC article.

2

The beta clamp targets DNA polymerase IV to DNA and strongly increases its processivity.

Wagner J, Fujii S, Gruz P, Nohmi T, Fuchs RP. Wagner J, et al. Among authors: nohmi t. EMBO Rep. 2000 Dec;1(6):484-8. doi: 10.1093/embo-reports/kvd109. EMBO Rep. 2000. PMID: 11263491 Free PMC article.

3

Erroneous incorporation of oxidized DNA precursors by Y-family DNA polymerases.

Shimizu M, Gruz P, Kamiya H, Kim SR, Pisani FM, Masutani C, Kanke Y, Harashima H, Hanaoka F, Nohmi T. Shimizu M, et al. Among authors: nohmi t. EMBO Rep. 2003 Mar;4(3):269-73. doi: 10.1038/sj.embor.embor765. EMBO Rep. 2003. PMID: 12634844 Free PMC article.

4

Catalytic and non-catalytic roles of DNA polymerase κ in the protection of human cells against genotoxic stresses.

Kanemaru Y, Suzuki T, Niimi N, Grúz P, Matsumoto K, Adachi N, Honma M, Nohmi T. Kanemaru Y, et al. Among authors: nohmi t. Environ Mol Mutagen. 2015 Oct;56(8):650-62. doi: 10.1002/em.21961. Epub 2015 Jul 21. Environ Mol Mutagen. 2015. PMID: 26031400

5

The role of DNA polymerase ζ in translesion synthesis across bulky DNA adducts and cross-links in human cells.

Suzuki T, Grúz P, Honma M, Adachi N, Nohmi T. Suzuki T, et al. Among authors: nohmi t. Mutat Res. 2016 Sep-Oct;791-792:35-41. doi: 10.1016/j.mrfmmm.2016.08.004. Epub 2016 Aug 25. Mutat Res. 2016. PMID: 27591392

6

Limited ability of DNA polymerase kappa to suppress benzo[a]pyrene-induced genotoxicity in vivo.

Masumura K, Toyoda-Hokaiwado N, Niimi N, Grúz P, Wada NA, Takeiri A, Jishage KI, Mishima M, Nohmi T. Masumura K, et al. Among authors: nohmi t. Environ Mol Mutagen. 2017 Dec;58(9):644-653. doi: 10.1002/em.22146. Epub 2017 Oct 27. Environ Mol Mutagen. 2017. PMID: 29076178

7

Error-prone bypass patch by a low-fidelity variant of DNA polymerase zeta in human cells.

Suzuki T, Sassa A, Grúz P, Gupta RC, Johnson F, Adachi N, Nohmi T. Suzuki T, et al. Among authors: nohmi t. DNA Repair (Amst). 2021 Apr;100:103052. doi: 10.1016/j.dnarep.2021.103052. Epub 2021 Feb 3. DNA Repair (Amst). 2021. PMID: 33607474

8

The steric gate amino acid tyrosine 112 is required for efficient mismatched-primer extension by human DNA polymerase kappa.

Niimi N, Sassa A, Katafuchi A, Grúz P, Fujimoto H, Bonala RR, Johnson F, Ohta T, Nohmi T. Niimi N, et al. Among authors: nohmi t. Biochemistry. 2009 May 26;48(20):4239-46. doi: 10.1021/bi900153t. Biochemistry. 2009. PMID: 19341290

9

Phenylalanine 171 is a molecular brake for translesion synthesis across benzo[a]pyrene-guanine adducts by human DNA polymerase kappa.

Sassa A, Niimi N, Fujimoto H, Katafuchi A, Grúz P, Yasui M, Gupta RC, Johnson F, Ohta T, Nohmi T. Sassa A, et al. Among authors: nohmi t. Mutat Res. 2011 Jan 10;718(1-2):10-7. doi: 10.1016/j.mrgentox.2010.11.002. Epub 2010 Nov 13. Mutat Res. 2011. PMID: 21078407

10

In vivo evidence that DNA polymerase kappa is responsible for error-free bypass across DNA cross-links induced by mitomycin C.

Takeiri A, Wada NA, Motoyama S, Matsuzaki K, Tateishi H, Matsumoto K, Niimi N, Sassa A, Grúz P, Masumura K, Yamada M, Mishima M, Jishage KI, Nohmi T. Takeiri A, et al. Among authors: nohmi t. DNA Repair (Amst). 2014 Dec;24:113-121. doi: 10.1016/j.dnarep.2014.09.002. Epub 2014 Oct 7. DNA Repair (Amst). 2014. PMID: 25303778

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